Evidence map›Paper›PMID 41261134›Full record

ArticleNature2026

The asymmetric synthesis of an acyclic N-stereogenic amine.

Chendan Zhu, Sayantani Das, Marie Sophie Sterling, Nobuya Tsuji, Spencer J Léger, Frank Neese, Chandra Kanta De, Benjamin List

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chendan Zhu *Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany.ORCID http://orcid.org/0000-0003-0213-3205
Sayantani Das *Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany.
Marie Sophie SterlingMax-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany.
Nobuya TsujiInstitute for Chemical Reaction Design and Discovery (ICReDD), Hokkaido University, Sapporo, Japan.ORCID http://orcid.org/0000-0003-3226-6201
Spencer J LégerMax-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany.ORCID http://orcid.org/0000-0002-2912-7705
Frank NeeseMax-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany.ORCID http://orcid.org/0000-0003-4691-0547
Chandra Kanta DeMax-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany. de@kofo.mpg.de.ORCID http://orcid.org/0000-0001-6432-1610
Benjamin ListMax-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany. list@kofo.mpg.de.ORCID http://orcid.org/0000-0002-9804-599X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most molecules in chemistry and biology are chiral, leading to mirror-image variants, so-called enantiomers. However, although the selective chemical synthesis of molecules in which the stereogenicity arises from a carbon atom is well-established, enantioselective approaches to nitrogen-stereogenic molecules are much less common

Identifiers

PMID41261134
PMCPMC12804080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.