Evidence map›Paper›PMID 41261130›Full record

ArticleNature2026

Repulsions instruct synaptic partner matching in an olfactory circuit.

Zhuoran Li, Cheng Lyu, Chuanyun Xu, Ying Hu, David J Luginbuhl, Asaf B Caspi-Lebovic, Jessica M Priest, Engin Özkan, Liqun Luo

Erratum issuedAbstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Zhuoran Li *Department of Biology and Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.ORCID 0009-0007-2979-5678
Cheng Lyu *Department of Biology and Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.ORCID 0000-0003-2921-3061
Chuanyun XuDepartment of Biology and Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.ORCID 0009-0002-1138-871X
Ying HuDepartment of Biology and Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
David J LuginbuhlDepartment of Biology and Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.ORCID 0000-0002-2142-780X
Asaf B Caspi-LebovicDepartment of Biochemistry and Molecular Biology, The Neuroscience Institute and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.ORCID 0009-0004-5420-7506
Jessica M PriestDepartment of Biochemistry and Molecular Biology, The Neuroscience Institute and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.ORCID 0000-0001-7511-6284
Engin ÖzkanDepartment of Biochemistry and Molecular Biology, The Neuroscience Institute and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.ORCID 0000-0002-0263-6729
Liqun LuoDepartment of Biology and Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA. lluo@stanford.edu.ORCID 0000-0001-5467-9264

Funding

DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
Assembly of the Central Olfactory Networks in DrosophilaR01DC005982 · NIDCD · STANFORD UNIVERSITY · PI LIQUN LUO · 2003 to 2026
$8.1M
Mechanistic studies of molecular recognition and signaling of neuronal wiring receptorsR01NS139060 · NINDS · UNIVERSITY OF CHICAGO · PI Robert Arnulfo Carrillo, Engin Ozkan · 2024 to 2026
$1.5M
NIDCD NIH HHS R01 DC005982NIH HHS P40 OD010949NINDS NIH HHS R01 NS139060
6 · The paper itself

Abstract

Neurons exhibit extraordinary precision in selecting synaptic partners. Although cell-surface proteins (CSPs) that mediate attractive interactions between developing axons and dendrites have been shown to instruct synaptic partner matching

Indexed as

Drosophila melanogasterOlfactory PathwaysOlfactory Receptor NeuronsSynapsesAnimalsAxonsDendritesDrosophila ProteinsFemaleMaleMembrane ProteinsSingle-Cell AnalysisDrosophila ProteinsMembrane Proteins

Identifiers

PMID41261130
PMCPMC12804089

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.