ArticleNature2025
A skin-permeable polymer for non-invasive transdermal insulin delivery.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Macropinocytosis-mediated recyclable LYTACs (McR-TACs) for receptor-independent protein degradation.Nature biotechnology · 2026Article
- The Needle-Free Frontier: Redefining the Limits of Transdermal Insulin Delivery.Exploration (Beijing, China) · 2026Article
- Amine oxide lipid nanoparticles for delivery of cyclic dinucleotides.National science review · 2026Article
- Nanomaterial-driven modulation of lipid metabolism: Novel strategies toward precision obesity treatment.Bioactive materials · 2026Review
- Zwitterion-Based Polymeric Carriers for Efficient Drug Delivery across Biological Barriers.Polymer science & technology (Washington, D.C.) · 2026Review
- Mucus and tumor penetrating paclitaxel micelles for potent local therapy of cervical cancer.Journal of nanobiotechnology · 2026Article
- Nanotechnologies for Skin Drug Delivery: Polymeric, Bio-Based, and Hybrid Nanocarriers with Clinical and Translational Perspectives.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Universal diseased-site targeting via glycolysis-driven lactic acid gradient.Science advances · 2026Article
- Oral Poly(N-oxide) zwitterionic nanoplatform for Gambogenic Acid Enhances Mucosal penetration for potentiated anti-angiogenic therapy.International journal of pharmaceutics: X · 2026Article
- Fluorous oligoarginines as supra-enhancers for intracellular and transdermal peptide delivery.Bioactive materials · 2026Article
- Advances in Insulin Delivery: Transdermal and Needle-Free Technologies as Emerging Strategies to Improve Metabolic Control and Treatment Adherence.Life (Basel, Switzerland) · 2026Review
- Material-driven glucose responsiveness in insulin delivery systems: carrier selection and performance.Frontiers in endocrinology · 2026Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Qiuyu Wei *Zhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Zhi He *Institute of Quantitative Biology, Zhejiang Key Laboratory of Cell and Molecular Intelligent Design and Development, College of Life Science, Zhejiang University, Hangzhou, China.
Zifan Li *Zhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Zhuxian Zhou *Zhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.ORCID 0000-0002-7104-9915
Ying PiaoZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Jianxiang HuangInstitute of Quantitative Biology, Zhejiang Key Laboratory of Cell and Molecular Intelligent Design and Development, College of Life Science, Zhejiang University, Hangzhou, China.
Yu GengZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.ORCID 0000-0001-7615-7950
Runnan ZhangZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Yaqi FuInstitute of Quantitative Biology, Zhejiang Key Laboratory of Cell and Molecular Intelligent Design and Development, College of Life Science, Zhejiang University, Hangzhou, China.
Jiayi YeZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Yue YuanZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.ORCID 0009-0007-8990-2199
Haoru ZhuZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Jiaheng ZengZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Yan ZhangZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Quan ZhouZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.ORCID 0000-0002-6252-0154
Mingyu XuInstitute of Quantitative Biology, Zhejiang Key Laboratory of Cell and Molecular Intelligent Design and Development, College of Life Science, Zhejiang University, Hangzhou, China.ORCID 0009-0007-8671-2330
Shiqun ShaoZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.ORCID 0000-0001-7029-3791
Jianbin TangZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Jiajia XiangZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China. xiang_jj@zju.edu.cn.ORCID 0000-0001-5404-0735
Rongjun ChenDepartment of Chemical Engineering, Imperial College London, London, UK. rongjun.chen@imperial.ac.uk.ORCID 0000-0002-8133-5472
Ruhong ZhouInstitute of Quantitative Biology, Zhejiang Key Laboratory of Cell and Molecular Intelligent Design and Development, College of Life Science, Zhejiang University, Hangzhou, China. rhzhou@zju.edu.cn.ORCID 0000-0001-8624-5591
Youqing ShenZhejiang Key Laboratory of Smart Biomaterials and Center for Bionanoengineering, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, State Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China. shenyq@zju.edu.cn.ORCID 0000-0003-1837-7976
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-invasive skin permeation is widely used for convenient transdermal delivery of small-molecule therapeutics (less than 500 Da) with appropriate hydrophobicities
Indexed as
Drug Delivery SystemsInsulinMethacrylatesPolymersSkinSkin AbsorptionAdministration, CutaneousAnimalsDermisDiabetes Mellitus, ExperimentalEpidermisFemaleHumansMaleMiceNylonsInsulinMethacrylatesNylonspoly(2-(dimethylamino)ethyl methacrylate)Polymers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.