ArticleThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians2025
Among patients undergoing induction who reach active phase, does prolonged latent phase matter?
Article in The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveWe sought to assess whether a prolonged latent phase is associated with increased risk of cesarean delivery (CD) and adverse outcomes among patients undergoing induction of labor (IOL) reaching the active phase. STUDY
designThis was a secondary analysis of a prospective cohort study from 2018-2022 of term, singleton gestations with intact membranes and unfavorable cervix undergoing IOL at two large academic hospitals. Patients who reached active labor (≥6cm dilation) were included. Prolonged latent phase was defined as <6 cm dilated after ≥12 h with ruptured membranes and oxytocin. The primary outcome was CD after reaching active phase. Secondary outcomes included CD for labor arrest and maternal/neonatal morbidity. Analyses were stratified by parity and mode of delivery, and multivariable logistic regression was performed to adjust for confounders.
resultsOf 8,509 patients, 7,451 (87.6%) reached active phase. Among them, 472 (6.3%) had a prolonged latent phase, with a median duration of 15.4 h [13.3-26.8]. 74.8% of patients who reached active labor after a prolonged latent phase delivered vaginally, though they had a higher rate of CD than those without a prolonged latent phase (25.2% vs 9.9%,
conclusionAmong term patients undergoing induction with an unfavorable cervix, patients with a prolonged latent phase who ultimately enter active labor have a high rate of vaginal delivery. However, a prolonged latent phase is associated with increased morbidity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.