Evidence map›Paper›PMID 41260646›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Enterotoxigenic Escherichia coli Type O6-related Cytoplasmic Anti-neutrophil Cytoplasmic Antibody-positive Necrotizing Glomerulitis Diagnosed by Indirect Immunofluorescence.

Hisashi Sugimoto, Naoki Sawa, Yuki Oba, Daisuke Ikuma, Akinari Sekine, Hiroki Mizuno, Masayuki Yamanouchi, Eiko Hasegawa, Tatsuya Suwabe, Kiho Tanaka and 5 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hisashi SugimotoNephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Naoki SawaNephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Yuki ObaNephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Daisuke IkumaNephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Akinari SekineNephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Hiroki MizunoNephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Masayuki YamanouchiNephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Eiko HasegawaNephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Tatsuya SuwabeNephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Kiho TanakaNephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.
Kei KonoDepartment of Pathology, Toranomon Hospital Toranomon, Japan.
Keiichi KinowakiDepartment of Pathology, Toranomon Hospital Toranomon, Japan.
Kenichi OhashiDepartment of Pathology, Toranomon Hospital Toranomon, Japan.
Yutaka YamaguchiYamaguchi's Pathology Laboratory, Japan.
Yoshifumi UbaraNephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two days after eating beef steak grilled rare, a 28-year-old man developed a fever, abdominal pain, and diarrhea. The diarrhea resolved after 5 days of ciprofloxacin treatment (200 mg). Stool cultures obtained at the time of the onset were subsequently confirmed as enterotoxigenic Escherichia coli type O6. However, the renal dysfunction worsened, and the patient developed proteinuria and urinary occult blood. A kidney biopsy revealed necrotizing glomerulonephritis in the majority of glomeruli. An enzyme-linked immunosorbent assay was negative for myeloperoxidase/proteinase 3 anti-neutrophil cytoplasmic antibody (ANCA), but indirect immunofluorescence (IIF) was positive for cytoplasmic ANCA (C-ANCA). This case suggests a relationship between necrotizing glomerulonephritis and IIF-positive C-ANCAs.

Indexed as

Antibodies, Antineutrophil CytoplasmicEnterotoxigenic Escherichia coliEscherichia coli InfectionsGlomerulonephritisAdultFluorescent Antibody Technique, IndirectHumansMaleAntibodies, Antineutrophil CytoplasmicANCAANCA-associated vasculitisenterotoxigenic Escherichia coliEscherichia coli infectionShiga toxin-producing Escherichia coli

Identifiers

PMID41260646
PMCPMC13349483

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.