Evidence map›Paper›PMID 41260609›Full record

ArticleJournal of microbiology and biotechnology2025

Simultaneous and Accurate Visual Detection of Vancomycin-Resistant Enterococci

Yuqing Xing, Tingting Hu, Siyi Zhou, Jilu Shen

Abstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuqing XingDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, P.R. China.
Tingting HuDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, P.R. China.
Siyi ZhouDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, P.R. China.
Jilu ShenDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vancomycin-resistant Enterococcus (VRE) has demonstrated increasing global prevalence in recent years. Clinical detection currently relies on phenotypic methods including agar screening, minimum inhibitory concentration (MIC) testing, Kirby-Bauer disk diffusion, and Etest. In addition, molecular approaches such as polymerase chain reaction (PCR) and quantitative PCR (qPCR) can be applied for VRE identification. Nevertheless, these methods cannot achieve point-of-care detection (POCT). Thus, novel rapid diagnostic platforms have become urgently needed for curbing VRE transmission and containing nosocomial outbreaks. Recombinase polymerase amplification (RPA) and lateral flow strips (LFS) are effective tools for achieving rapid POCT. In this study, RPA was combined with LFS to establish a fast, sensitive, and specific detection method. This study established a multiplex RPA-LFS (mRPA-LFS) that delivers results within 30-40 min, with detection limits of 10

Indexed as

Bacterial ProteinsCarbon-Oxygen LigasesMultiplex Polymerase Chain ReactionNucleic Acid Amplification TechniquesVancomycin-Resistant EnterococciGram-Positive Bacterial InfectionsHumansLimit of DetectionMicrobial Sensitivity TestsRecombinasesSensitivity and SpecificityVancomycin ResistanceBacterial ProteinsCarbon-Oxygen LigasesRecombinasesVanA ligase, BacteriaVanB protein, Enterococcuslateral flow stripsrapid detectionrecombinase polymerase amplificationVancomycin-resistant enterococci

Identifiers

PMID41260609
PMCPMC12640772

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.