ReviewCurrent opinion in biotechnology2025
Whole-cell and cell-free biosensor-driven metabolic engineering.
Review in Current opinion in biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Applications of synthetic biology in biomedicine.Molecular biomedicine · 2026Review
- Expanding salivary biomarker detection by creating a synthetic neuraminic acid sensor via chimeragenesis.Applied and environmental microbiology · 2026Article
- Strategies for Metabolic Engineering ofMolecules (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Metabolic engineering employs microbial cell factories to produce high-value products from low-cost feedstocks. Designing, optimizing, and evaluating biosynthetic pathways in microbial cell factories is essential, yet these processes remain time- and labor-intensive. Biosensors help metabolic engineers address this challenge by converting target metabolite concentrations into observable outputs, enabling efficient assessment of microbial production. Whole-cell biosensors, which operate within living microorganisms, and cell-free biosensors, which function independently of cell growth using transcription-translation machinery, have contributed to microbial biosynthesis optimization through distinct approaches. This review summarizes recent advances in biosensor-driven metabolic engineering facilitated by whole-cell and cell-free biosensors.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.