ArticleScience advances2025
Far-red light orchestrates antiviral defense in plants.
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Light undergoes dramatic spectral shifts at dusk (sunset) and dawn (sunrise), enhancing insect activity and increasing the risk of insect-borne virus transmission. However, how plants respond to these light changes and associated viral threats remains unclear. Here, we show that far-red (FR) light, enriched in skylight during dusk and dawn, activates plant antiviral defense via phytochrome A (phyA). FR light-induced phyA activation promotes degradation of phytochrome interacting factor 1 (PIF1), which triggers the REVEILLE 7 (RVE7)-enhanced disease susceptibility 1 (EDS1) cascade to enhance salicylic acid (SA) signaling. Furthermore, multiple viruses use their RNA-dependent RNA polymerases to disrupt the phyA-far-red elongated hypocotyl 1 (FHY1) interaction to block phyA nuclear transport, impairing FR light-induced plant defense. Our findings uncover the molecular basis of FR light-mediated plant antiviral defense and reveal a previously unidentified viral counter-defense mechanism, highlighting how plants interpret environmental light cues to adapt to insect-borne viral infections.
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