ArticleBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2025
Retrospective evaluation of the PRE-DELIRIC score in a Chinese mixed ICU: implications for nursing practice.
Article in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Delirium is a common complication in intensive care units (ICU). The PRE-DELIRIC model has shown promise in early delirium prediction, but its performance in Chinese ICU settings remains unclear. The objective of this study was to validate the PRE-DELIRIC model in a Chinese mixed medical-surgical ICU and evaluate its utility in guiding nursing interventions for delirium prevention. In this single-center retrospective cohort study, adult patients admitted to the ICU between January 2023 and October 2024 were included. The PRE-DELIRIC score was calculated within 24 h of admission. Delirium was assessed using Confusion Assessment Method for the ICU (CAM-ICU) every 8 h. Model discrimination was assessed using the area under the receiver operating characteristic curve (AUROC). Among 580 patients, 176 (30.4%) developed delirium. The model showed good discrimination (AUROC 0.84; 95%CI: 0.81-0.87) and calibration (Hosmer-Lemeshow χ2=8.96, P=0.34). At the optimal cut-off point of 30%, sensitivity was 81.8% and specificity 78.2%, with 90.8% negative predictive value. Performance remained consistent across surgical (AUROC 0.84), medical (AUROC 0.86), and trauma patients (AUROC 0.85). Delirious patients had longer ICU stays (median 11.2 vs 7.1 days, P<0.001) and higher mortality (15.9 vs 10.4%, P=0.028). The PRE-DELIRIC model demonstrated reliable predictive performance in Chinese ICU settings. Integration into routine nursing assessment could guide individualized preventive interventions and optimize resource utilization.
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