Evidence map›Paper›PMID 41259351›Full record

ArticlePloS one2025

Development of the advised protocol for OCT study terminology and elements anterior segment OCT extension reporting guidelines (APOSTEL-AS): Study protocol.

Ameenat Lola Solebo, Marcus Ang, Alice Bellchambers, Colin J Chu, Alastair K Denniston, Laura E Downie, Thomas Evans, Alexander S Fraser, Scott Hau, Alex S Huang and 8 more

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ameenat Lola SoleboPopulation, Policy and Practice Department, UCL GOS Institute of Child Health, London, United Kingdom.ORCID https://orcid.org/0000-0002-8933-5864
Marcus AngCornea and External Eye Disease Service and Refractive Service, Singapore National Eye Center, Singapore, Singapore.
Alice BellchambersPopulation, Policy and Practice Department, UCL GOS Institute of Child Health, London, United Kingdom.
Colin J ChuMoorfields NIHR Biomedical Research Centre, London, United Kingdom.ORCID https://orcid.org/0000-0003-2088-8310
Alastair K DennistonNIHR Birmingham Biomedical Research Centre, Birmingham, United Kingdom.
Laura E DownieDepartment of Optometry and Vision Sciences, The University of Melbourne, Parkville, Victoria, Australia.ORCID https://orcid.org/0000-0002-1596-2259
Thomas EvansDepartment of Ophthalmology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.ORCID https://orcid.org/0009-0004-5193-0467
Alexander S FraserTrinidad Eye Hospital, San Fernando, Trinidad and Tobago.ORCID https://orcid.org/0009-0004-2871-7764
Scott HauMoorfields NIHR Biomedical Research Centre, London, United Kingdom.ORCID https://orcid.org/0000-0001-6913-6107
Alex S HuangHamilton Glaucoma Center, The Viterbi Family Department of Ophthalmology, Shiley Eye Institute, University of California, San Diego, California, United States of America.
Pearse A KeaneMoorfields NIHR Biomedical Research Centre, London, United Kingdom.ORCID https://orcid.org/0000-0002-9239-745X
Xiaoxuan LiuNIHR Birmingham Biomedical Research Centre, Birmingham, United Kingdom.
Jodhbir S MehtaCornea and External Eye Disease Service and Refractive Service, Singapore National Eye Center, Singapore, Singapore.
Giovanni OmettoUniversity Hospitals Sussex NHS Foundation Trust, London, United Kingdom.
Axel PetzoldMoorfields NIHR Biomedical Research Centre, London, United Kingdom.ORCID https://orcid.org/0000-0002-0344-9749
Edmund TsuiOcular Inflammatory Disease Center, UCLA Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America.
Tamara S FraserMid South Essex NHS Foundation Trust, Essex, United Kingdom.
Benjamin XuUSC Roski Eye Institute, Keck School of Medicine at USC, Los Angeles, California, United States of America.

Funding

Department of Health CS-2018-18-ST2-005Wellcome Trust 311252
6 · The paper itself

Abstract

backgroundAnterior segment optical coherence tomography (AS-OCT) is emerging as a valuable diagnostic, monitoring and predictive tool. Clinical utility has been suggested for ophthalmic disorders such as glaucoma, corneal disease, cataract and uveitis, which taken together comprise the majority of the blinding conditions affecting working age individuals globally. anterior segment is an obstacle to reproducibility and interoperability. To provide this guidance, we aim to extend the existing Advised Protocol for OCT Study Terminology and Elements (APOSTEL) guidelines, to ensure applicability to AS-OCT.

methodsIn line with EQUATOR Network guidance for the development of reporting guidelines, APOSTEL-AS will be developed through a staged consensus process involving literature review and Delphi consensus across an international multi-disciplinary stakeholder group, overseen by a multi-disciplinary multi-national Steering Committee. The systematic scoping review will be used to generate candidate items, support the development of a consensus nomenclature for AS-OCT representation of ocular structure, and to form Delphi group membership. Delphi methodology, used to consider items for inclusion, rewording or exclusion, will be undertaken in line with ACCORD (ACcurate COnsensus Reporting Document) guidance, with at least two rounds of Delphi survey, inclusion consensus threshold set at 80%, and steering committee reviews between rounds. The resultant APOSTEL-AS guideline will undergo piloting before dissemination of the final version. DISCUSSION: The APOSTEL-AS checklist, with minimum and recommended items to be reported about study methods, should provide timely support for researchers to ensure future standardisation, interoperability and reproducibility of reported work, hastening implementation and the translation of knowledge into clinically beneficial action.

Indexed as

Anterior Eye SegmentEye DiseasesTerminology as TopicTomography, Optical CoherenceConsensusDelphi TechniqueGuidelines as TopicHumansResearch Design

Identifiers

PMID41259351
PMCPMC12629414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.