Evidence map›Paper›PMID 41259246›Full record

ArticleJournal of the International Association of Providers of AIDS Care

Progressive Multifocal Leukoencephalopathy in a Young Male With Concurrent Neurosyphilis and HIV Infection: A Case Report.

Chunyan Zhang, Lijun Cao, Rulin Mi

Abstract readCase Reports
In one paragraph

Article in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chunyan ZhangDepartment of Neurology, Second Hospital, Shanxi Medical University, Taiyuan, Shanxi, China.ORCID 0000-0003-3936-3450
Lijun CaoDepartment of Neurology, Second Hospital, Shanxi Medical University, Taiyuan, Shanxi, China.
Rulin MiDepartment of Neurology, Second Hospital, Shanxi Medical University, Taiyuan, Shanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundThe co-infection of human immunodeficiency virus (HIV) and neurosyphilis presents a significant clinical challenge due to the increased risk of opportunistic infections, including progressive multifocal leukoencephalopathy (PML).Case PresentationA 23-year-old unmarried male with an unprotected sexual history presented with progressive right upper limb weakness and slurred speech for 10 days. He was diagnosed with HIV and neurosyphilis co-infection, and neuroimaging/cerebrospinal fluid studies confirmed PML.ConclusionsThis case highlights the importance of screening for HIV and neurosyphilis in young patients with neurological symptoms and the need for awareness of opportunistic infections such as PML in immunocompromised individuals.

Indexed as

CoinfectionHIV InfectionsLeukoencephalopathy, Progressive MultifocalNeurosyphilisHumansMagnetic Resonance ImagingMaleYoung Adulthuman immunodeficiency virusJC polyomavirusneurological complicationsneurosyphilisprogressive multifocal leukoencephalopathysyphilis

Identifiers

PMID41259246
PMCPMC12635037

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.