Evidence map›Paper›PMID 41259220›Full record

ArticleeLife2025

Conduction pathway for potassium through the

Adel Hussein, Xihui Zhang, Bjørn P Pedersen, David L Stokes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Lipids are essential for potassium transport by KdpFABC from E. coli.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Adel HusseinDepartment of Biochemistry and Molecular Pharmacology, NYU School of Medicine, New York, United States.
Xihui ZhangDepartment of Biochemistry and Molecular Pharmacology, NYU School of Medicine, New York, United States.
Bjørn P PedersenDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.
David L StokesDepartment of Biochemistry and Molecular Pharmacology, NYU School of Medicine, New York, United States.ORCID https://orcid.org/0000-0001-5455-8163

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
Pacific Northwest Center for Cryo-EM: Equipment SupplementR24GM154185 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI James E Evans, CLAUDIA SUSANA LOPEZ · 2024 to 2026
$21.5M
Transport Cycle and Inhibition of Human Na+-dicarboxylate Cotransporter NaDC3R01NS108151 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DANENG WANG · 2018 to 2026
$4.1M
Molecular Mechanisms of Ion Transport - Equipment supplementR35GM144109 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI David L. Stokes · 2022 to 2026
$3.2M
European Research Council 101000936NCI NIH HHS P30 CA016087NCI NIH HHS P30CA016087NIGMS NIH HHS R24 GM154185NIGMS NIH HHS R24GM154185NIGMS NIH HHS R35 GM144109NIGMS NIH HHS R35GM144109NINDS NIH HHS R01 NS108151NINDS NIH HHS R01NS108151Novo Nordisk Fonden NNF24OC0088380
6 · The paper itself

Abstract

Under osmotic stress, bacteria express a heterotetrameric protein complex, KdpFABC, which functions as an ATP-dependent K

Indexed as

Adenosine TriphosphatasesCation Transport ProteinsEscherichia coliEscherichia coli ProteinsPotassiumBinding SitesCryoelectron MicroscopyModels, MolecularProtein ConformationAdenosine TriphosphatasesCation Transport ProteinsEscherichia coli ProteinsPotassiumpotassium translocating Kdp-ATPase, E colicryo-EME. coliK channelmembrane transportmolecular biophysicsmutational analysisP-type ATPasestructural biology

Identifiers

PMID41259220
PMCPMC12629597

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.