Evidence map›Paper›PMID 41259139›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Glyceraldehyde-3-phosphate dehydrogenase homologs as bifunctional gatekeepers of metabolic segregation in

Nanqing Zhou, Caroll M Mendonca, Austin L Carroll, Stefan Pate, Manuel Nieto-Domínguez, Xinyu Chen, Lichun Zhang, Kelly P Teitel, Nienke K Dekker, Joshua R Elmore and 5 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Nanqing ZhouDepartment of Civil and Environmental Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL 60208.
Caroll M MendoncaDepartment of Civil and Environmental Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL 60208.
Austin L CarrollBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831.
Stefan PateDepartment of Chemical and Biological Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL 60208.ORCID 0000-0003-0500-6674
Manuel Nieto-DomínguezThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens, Lyngby 2800, Denmark.ORCID 0000-0001-8192-5176
Xinyu ChenDepartment of Civil and Environmental Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL 60208.
Lichun ZhangDepartment of the Geophysical Sciences, University of Chicago, Chicago, IL 60637.
Kelly P TeitelDepartment of Civil and Environmental Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL 60208.ORCID 0000-0001-9001-5369
Nienke K DekkerThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens, Lyngby 2800, Denmark.ORCID 0009-0001-5113-897X
Joshua R ElmoreBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831.ORCID 0000-0003-4750-9640
Pablo I NikelThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens, Lyngby 2800, Denmark.
Jacob R WaldbauerDepartment of the Geophysical Sciences, University of Chicago, Chicago, IL 60637.ORCID 0000-0002-0338-6143
Adam M GussBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831.
Niall M ManganDepartment of Engineering Sciences and Applied Mathematics, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL 60208.ORCID 0000-0002-3491-8341
Ludmilla AristildeDepartment of Civil and Environmental Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL 60208.ORCID 0000-0002-8566-1486

Funding

U.S. Department of Energy (DOE) DE-AC05-00OR22725U.S. Department of Energy (DOE) DE-SC0022181
6 · The paper itself

Abstract

Metabolically versatile

Indexed as

Bacterial ProteinsGlyceraldehyde-3-Phosphate DehydrogenasesPseudomonas putidaCitric Acid CycleGluconeogenesisGlucoseGlycolysisMetabolic Networks and PathwaysMetabolomeMetabolomicsBacterial ProteinsGlucoseGlyceraldehyde-3-Phosphate Dehydrogenasescarbon switchgluconeogenesisglycolysismetabolomicsproteomics

Identifiers

PMID41259139
PMCPMC12663938

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.