Evidence map›Paper›PMID 41259064›Full record

ArticleJournal of the National Cancer Institute2026

Tattoos and risk of cutaneous melanoma and nonmelanoma skin cancer in France.

Tingting Mo, Marie Zins, Marcel Goldberg, Céline Ribet, Sofiane Kab, Ines Schreiver, Katherina Siewert, Khaled Ezzedine, Joachim Schüz, Milena Foerster

Abstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Is tattooing associated with an increased risk of cancer? A systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  2. Tattoo practices and risk of hepatitis B and hepatitis C infection in the French Constances study.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tingting MoEnvironment and Lifestyle Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-8651-398X
Marie ZinsPopulation-based Cohorts Unit, INSERM UMS 11, Paris Saclay University, Paris, France.ORCID 0000-0002-4540-4282
Marcel GoldbergPopulation-based Cohorts Unit, INSERM UMS 11, Paris Saclay University, Paris, France.ORCID 0000-0002-6161-5880
Céline RibetPopulation-based Cohorts Unit, INSERM UMS 11, Paris Saclay University, Paris, France.ORCID 0000-0003-2174-1126
Sofiane KabPopulation-based Cohorts Unit, INSERM UMS 11, Paris Saclay University, Paris, France.ORCID 0000-0001-6041-9602
Ines SchreiverDermatotoxicology Study Centre, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.ORCID 0000-0001-9313-7193
Katherina SiewertDermatotoxicology Study Centre, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.ORCID 0000-0003-0380-1594
Khaled EzzedineDepartment of Dermatology, University Hospital Henri-Mondor, University of Paris Est-Créteil, Créteil, France.
Joachim SchüzEnvironment and Lifestyle Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-9687-2134
Milena FoersterEnvironment and Lifestyle Epidemiology Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0003-3912-1718

Funding

Caisse nationale d'assurance maladieFrench National Cancer Institute 2021-137French national health insurance fundFrench National Research Agency ANR-11-INBS-0002Infrastructure nationale en biologie et santéWorld Health Organization 001
6 · The paper itself

Abstract

backgroundWith the increasing popularity of decorative tattooing, which entails the intradermal injection of inks that may contain carcinogens, investigating the related potential skin cancer risk is a public health priority.

methodsWe used data from the Cancer Risk Attributable with the Body Art of Tattooing study, nested in the French national cohort Consultants des Centres d'Examens de Santé (adults aged 18-69 years recruited in 2012-2018). Tattoo exposure was collected in 2020-2023. Skin cancers overall, cutaneous melanoma, and nonmelanoma skin cancer diagnosed during 2007-2021 were retrieved from national health insurance data. As exposure was collected after possible disease ascertainment, risks of skin cancer with prior tattoo exposure were assessed using logistic regression and Cox proportional hazards models in a retrospective cohort design.

resultsAmong 111 074 participants, 1789 (1.6%) skin cancers were recorded (693 cutaneous melanoma, 1096 nonmelanoma skin cancer). No association was found between binary tattoo exposure (yes, no) and any skin cancer type. In the highest exposure category of tattoo body surface (>2 hand palms), 2 participants with skin cancer were observed among 1633 (0.1%) participants, yielding an odds ratio of 0.21 for overall skin cancer (95% confidence interval [CI] = 0.05 to 0.83; reference no tattoos); however, the corresponding Cox model was not statistically significant (hazard ratio [HR] = 0.26, 95% CI = 0.07 to 1.05).

conclusionsNo overall association between tattoo exposure and skin cancer was observed. The inverse association in the highest exposure category is based on very few skin cancer diagnoses and should be interpreted with caution. Further studies with larger number of participants with skin cancer more detailed exposure assessment are warranted.

Indexed as

Basal Cell CarcinomaMelanomaSkin NeoplasmsTattooingAdolescentAdultAgedFemaleFranceHumansMaleMiddle AgedRetrospective StudiesRisk FactorsYoung Adult

Identifiers

PMID41259064
PMCPMC13017047

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.