Evidence map›Paper›PMID 41258936›Full record

ArticleAnalytical chemistry2025

Ultra-Sensitive 3D Lateral Flow Assay Device for SARS-CoV-2 Detection Based on One-Step Dual-Signal Amplification.

Yi-Ru Chiou, Wei Wang, Yuh-Shiuan Chien, Cheng-Yang Tung, Wang-Huei Sheng, Chien-Fu Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi-Ru ChiouInstitute of Applied Mechanics, National Taiwan University, Taipei 106, Taiwan.
Wei WangInstitute of Applied Mechanics, National Taiwan University, Taipei 106, Taiwan.
Yuh-Shiuan ChienInstitute of Applied Mechanics, National Taiwan University, Taipei 106, Taiwan.ORCID 0009-0005-7095-8542
Cheng-Yang TungInstitute of Applied Mechanics, National Taiwan University, Taipei 106, Taiwan.
Wang-Huei ShengDivision of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei 106, Taiwan.
Chien-Fu ChenInstitute of Applied Mechanics, National Taiwan University, Taipei 106, Taiwan.ORCID 0000-0001-7459-1649

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A one-step nucleic acid lateral flow assay (NALFA) platform was developed for on-site detection of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), in which no additional operation step is required for signal amplification. Polyadenine (polyA) serves as an effective anchoring block for preferential binding with the gold nanoparticles (AuNPs) surface to form probes with a high density of DNA attachment. Furthermore, bimetallic deposition, which is Au deposition and Ag staining through subsequent reductions of Au

Indexed as

COVID-19Nucleic Acid Amplification TechniquesSARS-CoV-2ColorimetryGoldHumansLimit of DetectionMetal NanoparticlesRNA, ViralGoldRNA, Viral

Identifiers

PMID41258936
PMCPMC12874218

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.