Evidence map›Paper›PMID 41258887›Full record

ArticleMicrobial genomics2025

Population snapshot of

Kedibone Maria Ndlangisa, Cebile Lekhuleni, Happy Skosana, Linda de Gouveia, Susan Meiring, Sibongile Walaza, Vanessa Quan, Stephen D Bentley, Stephanie W Lo, Cheryl Cohen and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kedibone Maria NdlangisaNational Institute for Communicable Diseases (NICD), a Division of the National Health Laboratory Service, Johannesburg, South Africa.
Cebile LekhuleniNational Institute for Communicable Diseases (NICD), a Division of the National Health Laboratory Service, Johannesburg, South Africa.
Happy SkosanaNational Institute for Communicable Diseases (NICD), a Division of the National Health Laboratory Service, Johannesburg, South Africa.
Linda de GouveiaNational Institute for Communicable Diseases (NICD), a Division of the National Health Laboratory Service, Johannesburg, South Africa.
Susan MeiringNational Institute for Communicable Diseases (NICD), a Division of the National Health Laboratory Service, Johannesburg, South Africa.
Sibongile WalazaNational Institute for Communicable Diseases (NICD), a Division of the National Health Laboratory Service, Johannesburg, South Africa.
Vanessa QuanNational Institute for Communicable Diseases (NICD), a Division of the National Health Laboratory Service, Johannesburg, South Africa.
Stephen D BentleyPathogen and Microbes, Wellcome Trust Sanger Institute, Hinxton, UK.
Stephanie W LoPathogen and Microbes, Wellcome Trust Sanger Institute, Hinxton, UK.
Cheryl CohenNational Institute for Communicable Diseases (NICD), a Division of the National Health Laboratory Service, Johannesburg, South Africa.
Anne von GottbergNational Institute for Communicable Diseases (NICD), a Division of the National Health Laboratory Service, Johannesburg, South Africa.
Mignon du PlessisNational Institute for Communicable Diseases (NICD), a Division of the National Health Laboratory Service, Johannesburg, South Africa.

Funding

Southern African-Pittsburgh Public Health Genomic Epidemiology Training Program (SAPPHGenE)D43TW011255 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Lee H Harrison, Anne von Gottberg · 2019 to 2026
$1.7M
FIC NIH HHS D43 TW011255Gates Foundation INV-003570
6 · The paper itself

Abstract

Routine use of pneumococcal conjugate vaccines (PCV) in South Africa caused a decline in vaccine-associated invasive pneumococcal disease (IPD), followed by the emergence of non-PCV serotypes, driven mainly by pre-existing lineages. We determined the molecular epidemiology of isolates causing IPD among adults in South Africa from 2020 to 2025 before and following the implementation of PCV in 2009. We performed whole-genome sequencing on randomly selected isolates causing IPD among adults aged ≥18 years (

Indexed as

Pneumococcal InfectionsPneumococcal VaccinesStreptococcus pneumoniaeAdolescentAdultAgedFemaleGenome, BacterialHumansMaleMiddle AgedMolecular EpidemiologyMultilocus Sequence TypingSerogroupSouth AfricaVaccines, ConjugatePneumococcal VaccinesVaccines, Conjugateglobal pneumococcal sequence cluster (GPSC)pneumococcal conjugate vaccine (PCV)pneumococcus

Identifiers

PMID41258887
PMCPMC12668798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.