ArticleSurgery today2026
Real-world short-term outcomes after distal pancreatectomy with en bloc celiac axis resection using the National clinical database of Japan.
Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo identify the risk factors for mortality and morbidity after distal pancreatectomy with en bloc celiac axis resection (DP-CAR) using prospectively registered data from the National Clinical Database (NCD).
methodsWe retrospectively analyzed patients registered in the NCD between 2018 and 2021 who underwent DP-CAR. Surgical morbidity, mortality, and associated clinical factors were evaluated.
resultsThe study included 136 patients. Preoperative therapy included chemotherapy in 110 (80.9%) patients. The surgical mortality rate was 2.2% (3/136 patients). Recent weight loss (≥ 10% in the past 6 months) was significantly more prevalent in the mortality group than in the non-mortality group (33.3% [1/3] vs. 4.5% [6/133], respectively). Clavien-Dindo grade ≥ III complications occurred in 34.6% of the patients. Age ≥ 80 years old (odds ratio [OR], 8.75; 95% confidence interval [CI]: 1.21-63.43; p = 0.032) and portal vein resection (OR, 2.72; 95% CI: 1.04-7.13; p = 0.042) were identified as potential risk factors for severe postoperative complications. Recent weight loss (OR, 5.18; 95% CI: 0.96-27.8; p = 0.055) approached statistical significance.
conclusionAlthough specific mortality risk factors could not be identified, the low mortality rate suggests that DP-CAR is safely performed in Japanese practice. Future efforts should focus on achieving zero DP-CAR-associated mortality.
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