Evidence map›Paper›PMID 41258408›Full record

ArticleScientific reports2025

Assessment of cat exposure to phthalates through phthalate metabolites analysis in the hair samples.

Slawomir Gonkowski, Manolis Tzatzarakis, Elena Vakonaki, Thomas Lamprakis, Krystyna Makowska

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Evaluation of Cat Exposure to Bisphenol A (BPA) Using Hair Sample Analysis.Animals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Slawomir GonkowskiDepartment of Clinical Physiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-957, Olsztyn, Poland. Slawomir.gonkoski@uwm.edu.pl.
Manolis TzatzarakisLaboratory of Toxicology, School of Medicine, University of Crete, Heraklion, 71003, Crete, Greece.
Elena VakonakiLaboratory of Toxicology, School of Medicine, University of Crete, Heraklion, 71003, Crete, Greece.
Thomas LamprakisLaboratory of Toxicology, School of Medicine, University of Crete, Heraklion, 71003, Crete, Greece.
Krystyna MakowskaDepartment of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury, Olsztyn, Poland. krystyna.makowska@uwm.edu.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phthalates are substances used in industry which are harmful to humans and animals. Cats and dogs, living in close proximity to humans, are particularly exposed to the effects of phthalates. Although hair samples seem to be the best matrix for studies on long-term exposure to phthalates, no such studies have been conducted in cats to date. This study aimed to establish concentration levels of selected phthalate metabolites (i.e. monomethyl phthalate-MMP, monoethyl phthalate-MEP, mono-isobutyl phthalate-MiBP, monobutyl phthalate-MBP, monobenzyl phthalate-MBzP, mono-cyclohexyl phthalate-MCHP and mono(2-ethylhexyl) phthalate-MEHP) in cat hair samples using liquid chromatography with mass spectrometry (LC-MS/MS) analysis. MiBP and MEHP were found in 100% of samples with median 66.6 pg/mg and 35.9 pg/mg, respectively, MBP in 97.1% with median 55.7 pg/mg, MEP in 94.3% with median 152.0 pg/mg, MMP in 85.7% with median < limit of quantification (LOQ) and MBzP in 32.9% with median < limit of detection (LOD). MCHP has not been found in cat hair samples during this study. The study has shown that cats are exposed to phthalates. This exposure is higher in indoor cats and depends on the body condition. On the other hand, statistically significant gender- and age-dependent differences in phthalate metabolites levels have not been found during this study. The results have also shown that hair samples may be used as a matrix during studies on levels of phthalate metabolites in cats.

Indexed as

Environmental ExposureHairPhthalic AcidsAnimalsCatsChromatography, LiquidFemaleMaleTandem Mass Spectrometryphthalic acidPhthalic AcidsBiomonitoringCompanion animalsHairPetsPhthalates

Identifiers

PMID41258408
PMCPMC12630601

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.