Evidence map›Paper›PMID 41258211›Full record

ArticleSchizophrenia (Heidelberg, Germany)2025

Spontaneous head movements during virtual clinical interviews help predict 12-months clinical outcomes in youth at clinical high risk for psychosis.

Juliette Lozano-Goupil, Sophia Parmacek, James M Gold, Philip R Corlett, Gregory P Strauss, Jason Schiffman, Lauren M Ellman, Elaine F Walker, Albert Powers, Scott W Woods and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Schizophrenia (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Juliette Lozano-GoupilDepartment of Psychology, Northwestern University, Evanston, IL, USA. juliette.lozanogoupil@northwestern.edu.ORCID http://orcid.org/0000-0001-5919-7045
Sophia ParmacekDepartment of Psychology, Northwestern University, Evanston, IL, USA.
James M GoldMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Philip R CorlettDepartment of Psychiatry, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-5368-1992
Gregory P StraussDepartments of Psychology and Neuroscience, University of Georgia, Athens, GA, USA.
Jason SchiffmanDepartment of Psychological Science, 4201 Social and Behavioral Sciences Gateway, University of California, Irvine, CA, USA.
Lauren M EllmanDepartment of Psychology & Neuroscience, Temple University, Philadelphia, PA, USA.
Elaine F WalkerDepartment of Psychology and Program in Neuroscience, Emory University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-9798-8101
Albert PowersDepartment of Psychiatry, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-3057-5043
Scott W WoodsDepartment of Psychiatry, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-3103-5228
James A WaltzMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-9236-3719
Steven M SilversteinDepartments of Psychiatry, Neuroscience and Ophthalmology, University of Rochester Medical Center, Rochester, NY, USA.ORCID http://orcid.org/0000-0002-0699-0960
Vijay A MittalDepartment of Psychology, Northwestern University, Evanston, IL, USA.ORCID http://orcid.org/0000-0001-9017-5119

Funding

2/5 CAPER Computerized assessment of psychosis riskR01MH120088 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2020 to 2024
$2.0M
NIMH NIH HHS R01 MH120088U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) 1 R01 MH120088
6 · The paper itself

Abstract

Identifying predictors of clinical and functioning outcomes in individuals at clinical high risk (CHR) for psychosis is essential to early intervention and symptom monitoring. While motor abnormalities have been established as core features of psychosis vulnerability, the prognostic value of social motor behavior, particularly head movements during social interactions, remains underexplored despite being readily accessible and measurable by clinicians. We analyzed 10-minute of video recordings from virtual clinical interviews involving 72 individuals at CHR using an open-access video-based head tracking tool to quantify spontaneous head movements. In a longitudinal study, we examined associations between head movements, symptom severity, and global functioning at baseline and 12-month follow-up. At baseline, results showed that total amount of head movements were positively correlated with positive symptoms (ρ = 0.37), negative symptoms (ρ = 0.28), particularly social anhedonia (ρ = 0.30) and avolition (ρ = 0.31), and social functioning (ρ = -0.33). Head movements at baseline also predicted worsening of avolition (R

Identifiers

PMID41258211
PMCPMC12630965

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.