Evidence map›Paper›PMID 41258010›Full record

ArticleScientific reports2025

Dual role of ROS-dependent anti-cancer activity and photocatalytic degradation of graphene oxide against MCF-7 breast cancer cells and organic dye.

Chenthis Kanisha Chelliah, Govindan Rajivgandhi, Muthuchamy Maruthupandy, Gnanasekaran Chackaravarthi, Govindan Ramachandran, Yong-Hong Liu, Osama Abdalla Abdelshafy Mohamad, Shuai Li, Wen-Jun Li, Vijayabhaskara Rao Bhaviripudi and 3 more

RetractedAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Chenthis Kanisha ChelliahDepartment of Physics, B.S. Abdur Rahman Crescent Institute of Science and Technology, Vandalur, Tamil Nadu, 600048, India.
Govindan RajivgandhiState Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, People's Republic of China.
Muthuchamy MaruthupandyLab of Toxicology, Department of Health Sciences, The Graduate School of Dong-A University, 37, Nakdong-Dearo 550 Beon-Gil, Saha-Gu, Busan, 49315, South Korea.
Gnanasekaran ChackaravarthiLaboratorio de Nanocelulosa y Biomateriales, Departamento de Ingeniería Química, Biotecnología y Materiales, Facultad de Ciencias Físicas y Matemáticas, Universidad de Chile, Avenida Beauchef 851, 8370456, Santiago, Chile.
Govindan RamachandranLaboratorio de Nanocelulosa y Biomateriales, Departamento de Ingeniería Química, Biotecnología y Materiales, Facultad de Ciencias Físicas y Matemáticas, Universidad de Chile, Avenida Beauchef 851, 8370456, Santiago, Chile.
Yong-Hong LiuState Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, People's Republic of China.
Osama Abdalla Abdelshafy MohamadState Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, People's Republic of China.
Shuai LiState Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, People's Republic of China.
Wen-Jun LiState Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, People's Republic of China.
Vijayabhaskara Rao BhaviripudiDepartamento de Física, Facultad de Ciencias Naturales Matemática y del Medio Ambiente, Universidad Tecnológica Metropolitana, 7800002, Macul, Santiago, Chile.
S Sathik BashaDepartment of Physics, B.S. Abdur Rahman Crescent Institute of Science and Technology, Vandalur, Tamil Nadu, 600048, India. sathik.basha@crescent.education.
Kiran ShahapurkarCentre of Excellence- Advanced Materials Synthesis (CoE-AMS), Department of Mechanical Engineering, Alliance School of Applied Engineering, Alliance University, Bengaluru, 562106, India.
Gezahgn GebremaryamDepartment of Mechanical Engineering, Wolaita Sodo University, Wolaita Sodo, Ethiopia. gezahegngn2011@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene oxide (GO), a two-dimensional nanomaterial, was synthesized using a modified Hummers' method and evaluated for its dual biomedical and environmental applications. Structural characterization confirmed the successful formation of GO, as evidenced by XRD (d-spacing of 10.23 Å), FTIR (hydroxyl, epoxy, carboxyl, and carbonyl functional groups), TGA (distinct weight loss patterns), and microscopic analyses (FE-SEM, EDX, and HR-TEM) revealing spherical and rod-like morphologies. Biologically, GO exhibited potent cytotoxicity against MCF-7 breast cancer cells in a concentration-dependent manner. The IC

Indexed as

Antineoplastic AgentsBreast NeoplasmsColoring AgentsGraphiteReactive Oxygen SpeciesApoptosisCatalysisFemaleHumansMCF-7 CellsRhodaminesAntineoplastic AgentsColoring Agentsgraphene oxideGraphiteReactive Oxygen SpeciesRhodaminesAnti-cancer propertiesApoptotic cell death and mitochondrial damageGraphene oxideIn vitro inhibition

Identifiers

PMID41258010
PMCPMC12630849

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.