ArticleInternational journal for equity in health2025
Risk factors for catastrophic healthcare expenditure and high economic burden for children with anorectal malformations in Southwestern Uganda.
Article in International journal for equity in health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAnorectal malformations (ARMs) are common congenital anomalies in low-and middle-income countries (LMICs), and they are often repaired in a staged manner. High out-of-pocket (OOP) payment for surgical care in many LMICs makes households vulnerable to catastrophic health expenditures (CHE). ARM patients often require multiple operations and hospitalizations, which may make them vulnerable to CHE. In this study, we sought to determine the prevalence of CHE and the factors driving these costs among families of children with ARMs in southwestern Uganda.
methodsThis was a combined retrospective and prospective cohort study of the OOP and CHE among families of children with ARMs at a Regional Referral Hospital between June 2021 and July 2023. CHE was defined as a cost exceeding 10% of annual income. Patient characteristics were compared, and multivariable modeling with best subset analysis was used to determine which factors were significantly associated with CHE and total OOP expenditure.
resultsThere were 236 study participants with a median age at diagnosis of 6 days, 51% were male, 71% lived in rural areas, and the median distance traveled was 175 km. 64% of patients experienced CHE, with almost all families incurring travel costs (99%). Following best subset analysis, distance traveled (OR 1.06, 95% CI: 1.03-1.08) and rurality (OR 1.83, 95% CI: 0.96-3.48) were significantly associated with CHE, suggesting that for every additional 10 km, a patient traveled for care, there were 6% higher odds of incurring CHE. In examining total cost, patients who had a two-stage repair incurred more than twice the costs compared to those who had a single-stage repair, and education level and repair type were also significantly associated.
conclusionIdentifying methods to provide financial protection from CHE is essential for all children. ARM patients are at particularly high risk for CHE and high OPP expenditures, especially those living far from healthcare services and in rural areas.
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