ArticleTropical medicine and health2025
Insecticide resistance and malaria transmission indicators in Anopheles gambiae s.l. in Bobo-Dioulasso, Burkina Faso: implications for vector control strategies.
Article in Tropical medicine and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effects of a bloodless diet on fitness and malaria susceptibility in Anopheles mosquitoes from Burkina Faso.Scientific reports · 2026Article
- Targeting elongation factor 2 inFrontiers in insect science · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the context of intensified malaria control efforts in Burkina Faso, this study assessed i) the insecticide resistance status of Anopheles gambiae sensu lato and ii) key entomological indicators of malaria transmission in Bobo-Dioulasso.
methodsWorld Health Organization-standard susceptibility bioassays were conducted on Anopheles populations collected from six neighborhoods (Kua, Sarfalao, Sabaribougou, Dogona, Farakan and Kodeni). The bioassays tested six insecticides organochlorines (4%dichlorodiphenyltrichloroethane), organophosphates (1.25% pirimiphos-methyl), pyrethroids (0.75%permethrin, 0.05% deltamethrin, 0.05% alpha-cypermethrin), and carbamates (0.1% bendiocarb). Synergist bioassays using piperonyl butoxide (PBO) were also performed to investigate metabolic resistance mechanisms, and Plasmodium infection rates were determined via Polymerase Chain Reaction.
resultsOverall, data revealed high resistance levels to dichlorodiphenyltrichloroethane and pyrethroids, which are associated with moderate or higher frequencies of knockdown resistance mutations (L995F and L995S). Fortunately, a susceptibility to bendiocarb and pirimiphos-methyl was found in the majority of localities. The restoration of pyrethroid susceptibility following piperonyl butoxide pre-exposure suggests the involvement of metabolic resistance mechanisms. Analysis of 622 specimens from the Anopheles gambiae complex revealed a predominance of An. arabiensis (90.8%), followed by An. gambiae s.s. and An. coluzzii. Sporozoite infection rates varied by species, reaching 45% in An. coluzzii, 27.4% in An. arabiensis, and 16.2% in An. gambiae s.s. The overall entomological inoculation rate (EIR) was estimated at 10.6 infectious bites per person during the study period. Anopheles arabiensis contributed most of these bites (91.2%), highlighting its central role in malaria transmission in Bobo-Dioulasso.
conclusionsDespite insecticide resistance, Anopheles populations exhibited high Plasmodium infection rates, indicating ongoing transmission. These findings emphasize the urgent need for sustained entomological surveillance and resistance management to guide and optimize insecticide-based malaria control strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.