Evidence map›Paper›PMID 41257770›Full record

ArticleTropical medicine and health2025

Diphtheria outbreak in Somalia: a weekly sitrep on the recent health crisis-2025.

Saadaq Adan Hussein, Marian Muse Osman, Mohamed Mohamoud Hassan, Yahye Sheikh Abdulle Hassan, Abdirahman Aden Hussein, Rage Adem, Mohamed M Ali Fuje, Ayan Nur Ali, Abdinur Hussein Mohamed, Khadar Hussein Mohamud and 5 more

Abstract read
In one paragraph

Article in Tropical medicine and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Saadaq Adan HusseinDepartment of School of Postgraduate Studies, Benadir University, Hodan Benadir, Mogadishu, Somalia. sadakadamh@gmail.com.ORCID http://orcid.org/0009-0002-7097-8066
Marian Muse OsmanDepartment Benadir Institute for Research and Development, Benadir University, Mogadishu, Somalia.
Mohamed Mohamoud HassanDepartment Office Rector at, Benadir University, Mogadishu, Somalia.
Yahye Sheikh Abdulle HassanDepartment of Medicine and Surgery, Jamhuriya University of Science and Technology, Mogadishu, Somalia.
Abdirahman Aden HusseinDepartment of Social and Human Capital Development Pillar, Office of the Prime Minister, Federal Republic, Mogadishu, Somalia.
Rage AdemDepartment Innovation Hub, Benadir University, Mogadishu, Somalia.
Mohamed M Ali FujeDepartment of School of Postgraduate Studies, Benadir University, Hodan Benadir, Mogadishu, Somalia.
Ayan Nur AliDepartment of Emergency, Mogadishu Somali Türkiye Training and Research Hospital, Mogadishu, Somalia.
Abdinur Hussein MohamedDepartment of School of Postgraduate Studies, Benadir University, Hodan Benadir, Mogadishu, Somalia.
Khadar Hussein MohamudDepartment Somali Development Research Institute (SODRI), Mogadishu, Somalia.
Abdirahman Moallim IbrahimDepartment Faculty of Medicine and Surgery, Jazeera University, Mogadishu, Somalia.
Mohamed Farah YusufDepartment of CEO, Tayo Institute for Research and Development, Mogadishu, Somalia.
Abdinur Adan HusseinDepartment of Civil Engineering at Amoud University, Borama, Somalia.
Abdullahi Mohamed MohamudDepartment Faculty of Medicine and Surgery, Jazeera University, Mogadishu, Somalia.
AbdulJalil Abdullahi AliDepartment of School of Postgraduate Studies, Benadir University, Hodan Benadir, Mogadishu, Somalia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global diphtheria incidence has fallen following widespread use of the diphtheria-tetanus-pertussis (DTP) vaccine; pockets of low coverage and disrupted health services continue to fuel outbreaks. Somalia, already challenged by conflict-related displacement and fragile health infrastructure, declared a national diphtheria outbreak on 19 August 2025. We analysed weekly case-based surveillance data reported through Somalia's Integrated Disease Surveillance and Response (IDSR) system and the DHIS2 electronic platform (Epi-weeks 1-33, 2025) on the platform. Vaccination-coverage trends were extracted from WHO/UNICEF Estimates of National Immunization Coverage (WUENIC, 2000-2024). Supplementary information was obtained from the Ministry of Health situation reports and partner briefs. By Epi-week 33 (ending 17 August 2025), 1811 suspected diphtheria cases (17 laboratory-confirmed) and 89 deaths were recorded (case-fatality rate 5%). Children < 5 years accounted for 56% of cases; 87% of patients had no documented diphtheria immunization. Weekly incidence accelerated sharply after Epi-week 20, with the largest surges in Puntland, South-West State and the Benadir Regional Administration. DTP-1 coverage increased from 40 to 60% (2000-2018) to 79% in 2022 but plateaued at 70% in 2024; DTP-3 coverage reached 71% in 2022 yet remains insufficient for herd protection. Despite targeted ring vaccination and distribution of diphtheria antitoxin (DAT), constrained vaccine and DAT supplies, insecurity, and access barriers hamper outbreak control. Somalia's diphtheria resurgence underscores how conflict, displacement, and uneven immunization can reverse hard-won gains against vaccine-preventable diseases. Closing routine-coverage gaps, guaranteeing timely DAT and antibiotic access, expanding real-time surveillance, and intensifying community engagement are urgent priorities to halt transmission and avert additional deaths. Prompt mobilization of national leadership, donors, and technical partners is essential to contain the outbreak and restore progress toward diphtheria elimination.

Indexed as

CorynebacteriumCrisisDiphtheriaHealthOutbreakPublicSomaliaVaccination

Identifiers

PMID41257770
PMCPMC12628885

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.