Evidence map›Paper›PMID 41257721›Full record

ArticleBMC veterinary research2025

Evaluating the efficacy of injectable antioxidant AD3EC on oxidative stress biomarkers in Raini cashmere goats.

Amirhossein Saeedian, Mohammad Mazrouei Sebdani, Mehrdad Shamsaddini Bafti, Najmeh Kargar

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Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amirhossein SaeedianDepartment of Veterinary Medicine, Islamic Azad University, B.C., Baft, Iran.
Mohammad Mazrouei SebdaniDepartment of Veterinary Medicine, Islamic Azad University, B.C., Baft, Iran. m.mazrouei@iau.ir.
Mehrdad Shamsaddini BaftiBiological Manufactures of Research & Production and Research & Technology Department, South East Branch, Razi Vaccine & Serum Research Institute, Kerman, Iran.
Najmeh KargarAgricultural Research, Education and Extension Organization (AREEO), Kerman, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe transition period in goats is a critical phase characterized by significant physiological and metabolic changes as they prepare for parturition and the onset of lactation. This study investigated the effects of injectable AD3EC vitamin as an antioxidant on oxidative stress markers in Raini cashmere goats during the transition period. Twenty Raini cashmere goats were randomly assigned to treatment and control groups. Key oxidative factors, including malondialdehyde (MDA), total antioxidant capacity (TAC), glutathione peroxidase (GPx), and superoxide dismutase (SOD), were measured at following time points: two weeks before parturition, one week before parturition, and one, two, and three weeks postpartum.

resultsThe results demonstrated that the treatment group consistently exhibited significantly lower MDA levels compared to controls at all measured time points (p < 0.001). Although TAC levels were higher in the control group, the administration of AD3EC vitamin showed a positive trend in managing oxidative stress during critical periods, particularly one week postpartum. Notably, the treatment group experienced an increase in GPx levels postpartum, highlighting the potential of AD3EC vitamin to stimulate antioxidant enzyme activity. Additionally, SOD levels demonstrated an initial increase prior to parturition (p < 0.001).

conclusionOur findings underscore the potential of AD3EC vitamin as an effective intervention for reducing oxidative stress and promoting overall health and resilience in Raini cashmere goats during the transition period. Future research should further explore the integration of AD3EC vitamin with other dietary strategies to optimize antioxidant defense mechanisms in livestock.

Indexed as

AntioxidantsGoatsOxidative StressAnimalsBiomarkersFemaleGlutathione PeroxidaseMalondialdehydeSuperoxide DismutaseAntioxidantsBiomarkersGlutathione PeroxidaseMalondialdehydeSuperoxide DismutaseAD3ECOxidative factorsRaini cashmere goatTransition period

Identifiers

PMID41257721
PMCPMC12629044

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.