Evidence map›Paper›PMID 41257674›Full record

ArticleBMC psychiatry2025

A multidisciplinary approach to establishing clozapine in a patient with schizophrenia and comorbid ASD: a case report.

Madelaine Bridges, Agostina Secchi, Eromona Whiskey, Sukhi Shergill

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Madelaine BridgesKent and Medway NHS and Social Care Partnership Trust, Hermitage Lane, Maidstone, Kent, UK.
Agostina SecchiKent and Medway NHS and Social Care Partnership Trust, Hermitage Lane, Maidstone, Kent, UK.
Eromona WhiskeyKent and Medway NHS and Social Care Partnership Trust, Hermitage Lane, Maidstone, Kent, UK. Eromona.Whiskey@slam.nhs.uk.
Sukhi ShergillKent and Medway NHS and Social Care Partnership Trust, Hermitage Lane, Maidstone, Kent, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is substantial symptom overlap in psychosis and autism spectrum disorder (ASD) and co-morbidity is common. In addition, antipsychotic response may be moderated by the co-occurrence. Individuals with ASD may be at greater risk of some clozapine adverse effects and occasionally, its use may be contra-indicated. CASE PRESENTATION: We present the case of a patient with ASD with psychosis unresponsive to multiple antipsychotics, but extra precaution was required with clozapine.

conclusionA multidisciplinary approach is required to establish clozapine in a patient with schizophrenia and ASD.

Indexed as

Antipsychotic AgentsAutism Spectrum DisorderClozapineSchizophreniaAdultComorbidityHumansMaleAntipsychotic AgentsClozapineAutism spectrum disorderCase reportClozapinePsychosisSchizophrenia

Identifiers

PMID41257674
PMCPMC12723936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.