Evidence map›Paper›PMID 41257654›Full record

ArticleBMC psychiatry2025

The relationship of sensory processing with ADHD and its co-occurring behavioural symptoms based on both undirected and directed network analysis.

Jing Li, Yuan Gao, Min Dong, Wenchen Wang, Haimei Li, Meirong Pan, Xinxin Yue, Ningning Liu, Qiujin Qian, Yufeng Wang and 1 more

Abstract read
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Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Jing Li *Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China.
Yuan Gao *Peking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
Min Dong *Peking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
Wenchen WangDepartment of Psychological Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Haimei LiPeking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
Meirong PanPeking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
Xinxin YuePeking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
Ningning LiuPeking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
Qiujin QianPeking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
Yufeng WangPeking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China.
Lu LiuPeking University Sixth Hospital, Institute of Mental Health, Beijing, 100191, China. liulupku@bjmu.edu.cn.

Funding

National Key Basic Research Program of China 973 program 2014CB846104National Key Research and Development Program of China 2024YFC3308303National Science Foundation of China 81873802; 81641163; 81571340
6 · The paper itself

Abstract

backgroundAttention-deficit hyperactivity/impulsivity disorder (ADHD) commonly co-occurs with sensory processing (SP), autistic traits (ATs), and oppositional defiant disorder (ODD). Our aim is to explore the relationships among SP, ADHD symptoms, ATs, and ODD symptoms in a large sample of children with ADHD and elucidate the potential role of sensory dysfunction in ADHD comorbidity patterns using symptomatic network analyses.

methodsA total of 2676 children with ADHD aged 6 to 11 years were recruited from Peking University Sixth Hospital. For all subjects, the ADHD symptom severity was rated using the ADHD Rating Scale, ODD symptom severity using the related items in the Children's Clinical Diagnostic Interview Scale, SP symptom severity using the Child Sensory Integration Scale, and ATs using related items in the CBCL. R 4.2.1 packages including mgm, qgraph, and bnlearn were used for network analysis.

resultsIn the Graphical Gaussian Model (GGM), the SP items were connected with ATs and ADHD core symptoms and positioned relatively high in the directed acyclic graph (DAG). ATs_S, located higher in the DAG, played an important role in communication in the network as a node for SP and ODD to exert their influence on ADHD, and ADHD items were downstream nodes seemingly dependent on SP nodes and ATs_S in the network.

conclusionsSP may be fundamental to the complex manifestations in children with ADHD, especially given its close relationship with ATs profiles. ATs_S might play an essential role in communication in this symptomatic network. These findings may help clarify possible relationships of different symptoms in ADHD and provide potential targeted interventions to improve core symptoms of ADHD as well as ATs and ODD symptoms. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Attention Deficit and Disruptive Behavior DisordersAttention Deficit Disorder with HyperactivityAutistic DisorderChildComorbidityFemaleHumansMaleSeverity of Illness IndexADHDAutistic traitsNetwork analysisOppositional defiant disorderSensory processing

Identifiers

PMID41257654
PMCPMC12751380

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