ArticleBMC geriatrics2025
Impact of nutritional status on mortality in geriatric patients with osteoporosis: a retrospective cohort study.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Associations between controlling nutritional status and mortality in osteoporosis: evidence from NHANES, 2005-2018.Calcified tissue international · 2026Observational
- Association between controlling nutritional status (CONUT) and all-cause mortality in elderly hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease: a retrospective cohort study.Frontiers in nutrition · 2026Article
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9 authors.
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Abstract
backgroundThis study investigated the relationship between mortality and numerous characteristics in geriatric patients with osteoporosis, including nutritional, clinical, anthropometric, and biochemical factors.
methodsThis retrospective cohort comprised geriatric patients diagnosed with osteoporosis between January 2016 and December 2019. Demographics, anthropometrics, comorbidities, laboratory results, bone mineral density (DEXA) analyses, fracture history, and mortality data were obtained. In addition, nutritional status, hand grip strength, and gait speed were measured. The Geriatric Depression Scale (GDS) was applied and nutritional status was assessed using multiple tools: Mini Nutritional Assessment (MNA) Short and Long Forms, Controlling Nutritional Status (CONUT), Geriatric Nutritional Risk Index (GNRI), and Prognostic Nutritional Index (PNI).
resultsAmong the 752 patients (mean age 75.3 ± 6.8 years, 69.7% female), the mortality rate was 18.1% during a median follow-up of 55 months. Nutritional assessments significantly predicted both fracture occurrence and mortality. Optimal cut-offs for predicting mortality were: MNA Short Form ≤ 11, MNA Long Form ≤ 24, CONUT > 1.5, GNRI ≤ 105.5, and PNI ≤ 49.9. Independent predictors of mortality included increasing age (p < 0.001), male sex (p = 0.005), higher body shape index (p = 0.006), slower gait speed (p = 0.001), MNA Long Form score ≤ 24 (p = 0.002), and PNI score ≤ 49.9 (p < 0.001).
conclusionMalnutrition is strongly associated with higher mortality risk in older osteoporosis patients. Early identification of malnutrition is critical to administering appropriate interventions, and our results show that malnutrition deserves greater attention to understand its broader impacts on outcomes in geriatric patients, particularly those with osteoporosis.
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