Evidence map›Paper›PMID 41257613›Full record

Trial reportBMC psychiatry2025

The dynamic interplay between anxiety-related, psychotic, and suicidal experiences: a qualitative study.

Patricia Gooding, Kamelia Harris, Sarah Peters, Gillian Haddock

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03114917 (A Psychological Intervention for Suicide Applied to Patents With Psychosis), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03114917 nacompletednot on this map

A Psychological Intervention for Suicide Applied to Patents With Psychosis: the CARMS Trial (Cognitive Approaches to Combatting Suicidality)

TypeinterventionalSponsorUniversity of ManchesterRan2017 to 2022Enrolled329ConditionsPsychosis, Suicide Prevention, SuicidalityArmsCognitive AppRoaches to coMbatting Suicidality (CARMS)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Patricia GoodingDivision of Psychology and Mental Health, School of Health Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK. patricia.gooding@manchester.ac.uk.
Kamelia HarrisDivision of Psychology and Mental Health, School of Health Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.
Sarah PetersDivision of Psychology and Mental Health, School of Health Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.
Gillian HaddockDivision of Psychology and Mental Health, School of Health Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.

Funding

Efficacy and Mechanism Evaluation Programme 13/161/25
6 · The paper itself

Abstract

backgroundSuicidal experiences are highly prevalent in people with non-affective psychosis, as are anxiety problems. Understanding the interplay between suicidal and anxiety-related experiences in people with psychosis has been somewhat neglected. The over-arching aim of the current study was to redress this gap using a qualitative approach.

methodsA secondary Framework Analysis was applied to qualitative interviews with 18 people with recent suicidal and psychotic experiences.

resultsQualitative analyses evidenced a complex dynamic between psychotic, anxiety-related, and suicidal experiences. An emotional and cognitive-emotional dynamic was central which reflected: (a) the prominence of fear; (b) the perceived relentlessness of mental health problems; (c) feeling overpowered, overwhelmed, thwarted, and defeated; (d) perceptions of no hope and no future; and (e) wanting an unlikely end to the trap of ‘mental illness’. Within the emotional and cognitive-emotional dynamic, two pathways were clearly discernible: i.a. direct influence of anxiety on suicidal experiences with psychosis exacerbating anxiety-related experiences; and ii. an explicit pathway between psychotic and suicidal experiences with anxiety worsening psychotic experiences. A third pathway captured a non-discernible ‘mixture’ of anxiety-related, psychotic, and suicidal experiences. A fourth pathway illustrated how depressed and low mood states could interact with psychosis and anxiety to trigger and/or worsen suicidal states of mind. IMPLICATIONS: It is vital to better understand the interplay between psychosis, anxiety-related, and suicidal experiences whilst conjointly developing suicide-focused psychological therapies so that they directly address ways in which different manifestations of anxiety interact with psychosis to lead to, and worsen, suicidal experiences.

trial registrationClinicalTrials.gov (NCT03114917), first submitted 29th March 2017 (29/03/2017), first submitted that met QC Criteria 10th April 2017, first posted 14th April 2017 (14/04/2017). ISRCTN (reference ISRCTN17776666 https://doi.org/10.1186/ISRCTN17776666 ); 5th June 2017, (05/06/2017). Registration was recorded prior to participant recruitment commencing.

Indexed as

AnxietyPsychotic DisordersSuicidal IdeationAdultFemaleHumansMaleMiddle AgedQualitative ResearchYoung AdultAnxietyDelusionsHallucinationsNon-affective psychosisParanoiaSchizophreniaSuicide

Identifiers

PMID41257613
PMCPMC12628620

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.