ArticleACS chemical neuroscience2025
Thin-Film Reference Electrodes for Fast-Scan Cyclic Voltammetry.
Article in ACS chemical neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- A Dual-Mode Neural Amplifier Array for Biopotential and FSCV-Based Neurochemical Measurements.Biosensors · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Electrochemical sensors rely on reference electrodes (REs) to provide stable potential standards, ensuring accurate and reliable detection. The development of biocompatible, stable, and miniaturized REs to replace conventional Ag/AgCl electrodes is crucial for translating electrochemical sensing for human applications. This study evaluates the performance of thin-film electrodes made from gold (Au), platinum (Pt), poly(3,4-ethylenedioxythiophene)-polystyrenesulfonate (PEDOT:PSS), and platinum-iridium (Pt-Ir) as REs for fast-scan cyclic voltammetry (FSCV), a widely used technique for real-time neurotransmitter detection. Using dopamine (DA) sensing as a model platform, our results demonstrate that Pt-Ir electrodes provide the necessary stable potential, low drift, and high reproducibility for FSCV sensing, even at a reduced size of 0.1 mm × 0.1 mm. Additionally, Pt-Ir exhibited performance comparable to Ag/AgCl electrodes across various pH levels and in the presence of biofouling agents. These findings highlight Pt-Ir as a promising alternative RE, with strong potential for integration into miniaturized electrochemical sensors for both preclinical and clinical applications.
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Registered trials
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