Evidence map›Paper›PMID 41257414›Full record

ArticleThe Cochrane database of systematic reviews2025

Sugammadex for reversing neuromuscular blockade in infants and children.

Christian K Raphael, Nizar El Bcherawi, Frida Atallah, Marc Moukarzel, Nayla Kassab, Thuraya HajAli, Lara Rizk, Ruby Dagher, Joanne Khabsa, Marie Aouad-Maroun

Abstract read
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In one paragraph

Article in The Cochrane database of systematic reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christian K RaphaelDepartment of Anesthesiology and Pain Medicine, American University of Beirut Medical Center, Beirut, Lebanon.ORCID 0009-0008-0132-2243
Nizar El BcherawiDepartment of Anesthesiology and Pain Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Frida AtallahDepartment of Anesthesiology and Pain Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Marc MoukarzelDepartment of Anesthesiology and Pain Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Nayla KassabDepartment of Anesthesiology and Pain Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Thuraya HajAliDepartment of Anesthesiology and Pain Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Lara RizkDepartment of Anesthesiology and Pain Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Ruby DagherDepartment of Anesthesiology and Pain Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Joanne KhabsaClinical Research Institute, American University of Beirut, Beirut, Lebanon.
Marie Aouad-MarounDepartment of Anesthesiology and Pain Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis is a protocol for a Cochrane Review (intervention). The objectives are as follows: The primary objective of this review is to evaluate the benefits and harms of sugammadex compared to other neuromuscular blockade reversal agents (neostigmine and pyridostigmine) in infants and children undergoing surgical procedures. A secondary objective is to assess whether these outcomes differ by age group, comorbidities, co-medications, or type of neuromuscular blocking agent.

Indexed as

gamma-CyclodextrinsNeuromuscular BlockadeNeuromuscular Nondepolarizing AgentsChildChild, PreschoolCholinesterase InhibitorsHumansInfantNeostigminePyridostigmine BromideRandomized Controlled Trials as TopicSugammadexSystematic Reviews as TopicCholinesterase Inhibitorsgamma-CyclodextrinsNeostigmineNeuromuscular Nondepolarizing AgentsPyridostigmine BromideSugammadex

Identifiers

PMID41257414
PMCPMC12628360

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.