Evidence map›Paper›PMID 41257246›Full record

ArticlePatient preference and adherence2025

Treatment Goals in Schizophrenia: Subgroup Analysis of a Survey in Matched Physician-Patient Pairs.

Gerhard Gründer, Philipp Bauknecht, Stefanie Schell, Karolina Leopold, Michael Paulzen, Stefan Leucht

Abstract read
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Article in Patient preference and adherence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Gerhard GründerDepartment of Molecular Neuroimaging, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.ORCID 0000-0001-7868-3903
Philipp BauknechtDr. Carl GmbH, Stuttgart, Germany.ORCID 0000-0003-0423-8158
Stefanie SchellKlinikum Blankenburg, Harzklinikum Dorothea Christiane Erxleben, Academic teaching hospital of Otto von Guericke University Magdeburg, Blankenburg, Germany.
Karolina LeopoldDepartment of Psychiatry and Psychotherapy, Vivantes Klinikum Am Urban, Berlin, Germany.
Michael PaulzenAlexianer Center for Mental Health, Aachen, Germany.ORCID 0000-0003-4198-5160
Stefan LeuchtDepartment of Psychiatry and Psychotherapy, TUM School of Medicine and Health, Technische Universität München, Munich, Germany.ORCID 0000-0002-4934-4352

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Schizophrenia is a complex disease that affects many aspects of the lives of people living with the disease. Therefore, many different treatment goals are possible. Treatment goals in schizophrenia may differ between patients and physicians. Here, we set out to explore whether there are subgroups in which differences between patient goals and treating psychiatrist's goals are especially marked, which would highlight the need for better dialogue between psychiatrists and patients belonging to these subgroups. Methods: In a survey, patients with schizophrenia and their treating psychiatrists were asked about treatment goals. To this end, questionnaires were sent to psychiatrists all over Germany. Psychiatrists were asked to rank and rate a prespecified set of treatment goals for up to 3 specific patients. Furthermore, these same patients were asked to rank and rate the goals for themselves. Responses are analyzed in subgroups of patients stratified by sex, disease duration (≤5 years/>5 years) and treatment by psychiatrists in private practice vs hospital-based psychiatrists. Results: We obtained answers from 28 physicians, 17 of which worked exclusively in private practice, and 80 patients. Of the patients, 13 had a disease duration ≤5 years, 31 were female, and 52 were treated by psychiatrists in private practice. Concordance between patients and their physicians was fairly high, and none of the subgroups (shorter/longer disease duration, male/female sex, treatment by psychiatrists in private practice vs hospital-based psychiatrists) stood out as markedly different from the total cohort. The most marked differences between patients and physicians regarded avoidance of different possible medication side effects. Conclusion: We did not find any major differences between the subgroups in this study. Overall, there was a high concordance of rankings and ratings of treatment goals. Patients tended to focus on different side effects than physicians, indicating that these should be discussed thoroughly when making a treatment decision.

Indexed as

patient-centeredschizophreniasurveytreatment goals

Identifiers

PMID41257246
PMCPMC12620593

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.