ArticleERJ open research2025
Airway response to mannitol among healthy subjects.
Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Little is known how subject characteristics affect the airway responsiveness to mannitol, what is the upper limit of a normal response, and what is the reproducibility of the response among healthy subjects. Methods: Mannitol testing was performed in 125 healthy, nonsmoking subjects with an age range of 18-82 years and an almost equal male-to-female ratio. 25 of them repeated the test. The airway response to mannitol was expressed as the final percentage fall in forced expiratory volume in 1 s (FEV Results: Neither age, gender, height, body mass index, atopy, nor baseline FEV Conclusion: The subject characteristics do not have a significant effect on the airway responsiveness to mannitol. Therefore, the same upper limits of a normal response can be used in all adult nonsmoking subjects. Among healthy subjects with very mild airway responsiveness to mannitol, FFALL and RDR are poorly reproducible.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.