Evidence map›Paper›PMID 41257146›Full record

ReviewCureus2025

The Biological Conservative Reconstruction (BIOCORN) Procedure: Redefining Surgical Treatment of Gastroesophageal Reflux Disease (GERD) and Hiatal Hernia Through Anatomical Preservation.

Mark Salib, John Salib, Matthew Phillips

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mark SalibSchool of Medicine, St. George's University School of Medicine, St. George's, GRD.
John SalibSchool of Medicine, St. George's University School of Medicine, St. George's, GRD.
Matthew PhillipsGeneral Surgery, Community First Medical Center, Chicago, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Biological Conservative Reconstruction (BIOCORN) procedure is a laparoscopic, anatomically conservative approach for managing gastroesophageal reflux disease and hiatal hernia. Unlike traditional wrap-based surgeries, BICORN restores the native gastroesophageal junction and angle of His without creating a restrictive wrap, preserving physiological functions such as belching and vomiting. This narrative review synthesized evidence from multiple studies identified through a comprehensive literature search using systematic selection and independent, blinded review to minimize bias. Clinical data indicate that BICORN provides high patient satisfaction, durable symptom relief, and effective reflux control while minimizing common postoperative complications, including dysphagia, gas-bloat syndrome, and impaired gastric emptying. Reported hernia recurrence rates vary, emphasizing the importance of careful patient selection and meticulous surgical technique. Postoperative assessments suggest preserved esophageal physiology despite minimal changes in lower esophageal sphincter pressures, supporting the procedure's anatomical and functional approach. Despite these positive outcomes, gaps remain in long-term efficacy data, direct comparisons with traditional antireflux techniques, and criteria for optimal patient selection. Future research should focus on controlled studies, long-term outcomes, and patient-reported measures to define BICORN's role as a physiologically conservative surgical option. This review highlights BICORN as a promising approach for patients seeking effective reflux management while maintaining natural anatomy and function.

Indexed as

anatomical restorationanti-reflux surgerybicorn procedurefundoplication alternativegastroesophageal refluxhiatal herniaminimally invasive surgeryphysiological function preservationsurgical innovation

Identifiers

PMID41257146
PMCPMC12622291

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.