ReviewCureus2025
The Biological Conservative Reconstruction (BIOCORN) Procedure: Redefining Surgical Treatment of Gastroesophageal Reflux Disease (GERD) and Hiatal Hernia Through Anatomical Preservation.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Biological Conservative Reconstruction (BIOCORN) procedure is a laparoscopic, anatomically conservative approach for managing gastroesophageal reflux disease and hiatal hernia. Unlike traditional wrap-based surgeries, BICORN restores the native gastroesophageal junction and angle of His without creating a restrictive wrap, preserving physiological functions such as belching and vomiting. This narrative review synthesized evidence from multiple studies identified through a comprehensive literature search using systematic selection and independent, blinded review to minimize bias. Clinical data indicate that BICORN provides high patient satisfaction, durable symptom relief, and effective reflux control while minimizing common postoperative complications, including dysphagia, gas-bloat syndrome, and impaired gastric emptying. Reported hernia recurrence rates vary, emphasizing the importance of careful patient selection and meticulous surgical technique. Postoperative assessments suggest preserved esophageal physiology despite minimal changes in lower esophageal sphincter pressures, supporting the procedure's anatomical and functional approach. Despite these positive outcomes, gaps remain in long-term efficacy data, direct comparisons with traditional antireflux techniques, and criteria for optimal patient selection. Future research should focus on controlled studies, long-term outcomes, and patient-reported measures to define BICORN's role as a physiologically conservative surgical option. This review highlights BICORN as a promising approach for patients seeking effective reflux management while maintaining natural anatomy and function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.