Evidence map›Paper›PMID 41257105›Full record

ArticleCureus2025

An Uncommon Presentation of Growing Teratoma Syndrome in a Patient Treated for Testicular Immature Teratoma: A Case Report.

Manal Lyagoubi, Nadir Miry, Nassira Karich, Anass Haloui, Amal Bennani

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manal LyagoubiPathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Nadir MiryPathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Nassira KarichPathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Anass HalouiPathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Amal BennaniPathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growing teratoma syndrome (GTS) is an uncommon post-chemotherapy event in non-seminomatous germ cell tumors and presents as enlarging masses composed of mature teratoma despite normalized markers. As systemic therapy is generally ineffective, treatment focuses on surgical excision. We report the case of a 30-year-old male with an immature teratoma of the right testis who, after completing chemotherapy with normalized tumor markers, developed enlarging lymph node masses histologically confirmed as mature teratoma, consistent with GTS. This case highlights the importance of maintaining a high index of suspicion for GTS in patients with immature teratomas undergoing chemotherapy and underscores the critical role of multidisciplinary follow-up to ensure timely diagnosis and effective management.

Indexed as

growing teratoma syndromemature teratomanon-seminomatous germ cell tumorteratomatesticular neoplasm

Identifiers

PMID41257105
PMCPMC12622764

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.