ArticleJournal of clinical practice and research2024
Mediterranean Fever (
Article in Journal of clinical practice and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Kawasaki Disease: Unraveling Immunopathogenesis, Genetic Factors, and AI Applications in Diagnosis with a Focus on Iran.Pediatric cardiology · 2026Review
- Relationship Between Clinical Manifestations of Acute Rheumatic Fever and Mutations in the FMF-AssociatedChildren (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Kawasaki Disease (KD) is a type of systemic vasculitis mediated by an abnormal immune response, similar to autoinflammatory disorders, due to increased release of proinflammatory cytokines. This cross-sectional study aims to evaluate the relationship between the frequency and severity of KD and the presence of Mediterranean Fever ( Materials and Methods: Thirty-eight children diagnosed with KD were included in the study. Demographic and clinical data such as age at diagnosis, gender, and duration of fever prior to intravenous immunoglobulin (IVIG) treatment were recorded. Laboratory and echocardiographic data at the time of diagnosis were also retrospectively reviewed. Results: The study comprised 38 patients, including 25 boys (65.8%) and 13 girls (34.2%), with a median age of 3.4 years (range 1.8-6.3 years). Coronary arterial lesions were observed in 11 patients (28.9%), and 13 patients (34.2%) were resistant to initial IVIG treatment. Twenty-two patients (57.9%) had at least one allele with MEFV variants. Of these, eight patients (36% of MEFV-positive patients) had at least one exon-10 variant, while 14 patients had only exon-2 variants. No statistically significant differences were found in clinical, demographic, or echocardiographic parameters between MEFV-positive and MEFV-negative patients. Conclusion: This study found that the presence of
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