Evidence map›Paper›PMID 41256851›Full record

ArticleFrontiers in immunology2025

Immunomodulatory effects of dietary methionine supplementation in rainbow trout (

Inês Carvalho, Felipe Bolgenhagen Schoninger, André Cunha, Diogo Peixoto, Francisca Brito, Luara Simões, Mariana Vaz, Allan Stensballe, Inês Ferreira, Paulo Santos and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Inês CarvalhoCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Matosinhos, Portugal.
Felipe Bolgenhagen SchoningerCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Matosinhos, Portugal.
André CunhaCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Matosinhos, Portugal.
Diogo PeixotoCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Matosinhos, Portugal.
Francisca BritoCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Matosinhos, Portugal.
Luara SimõesCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Matosinhos, Portugal.
Mariana VazCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Matosinhos, Portugal.
Allan StensballeDepartment of Health Science and Technology, University of Aalborg, Aalborg, Denmark.
Inês FerreiraCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Matosinhos, Portugal.
Paulo SantosCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Matosinhos, Portugal.
Carolina TafallaFish Immunology and Pathology Group, Biotechnology Department, National Institute for Agricultural and Food Research and Technology (INIA), Spanish National Research Council (CSIC), Madrid, Spain.
Marina MachadoCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Matosinhos, Portugal.
Benjamín CostasCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Matosinhos, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methionine, an essential amino acid, participates in various pathways with implications for the immune system. Recent evidence suggests that it may support both innate and adaptive immune mechanisms. In the present study, it was hypothesized that dietary methionine supplementation prior to vaccination may be a promising strategy to improve vaccine efficacy. Hence, the current research aimed to evaluate the effects of dietary methionine supplementation on the immune status of rainbow trout (

Indexed as

Bacterial VaccinesDietary SupplementsFish DiseasesMethionineOncorhynchus mykissYersinia InfectionsYersinia ruckeriAnimal FeedAnimalsImmunity, InnateVaccinationBacterial VaccinesMethionineamino acidsenteric redmouth diseasefish immunityfunctional ingredientsimmunization

Identifiers

PMID41256851
PMCPMC12620199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.