ArticleJournal of clinical practice and research2023
Skull Base Osteomyelitis Complicating COVID-19: A Novel Secondary Infection?
Article in Journal of clinical practice and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Data from the onset of the Coronavirus Disease 2019 (COVID-19) pandemic has revealed a broad spectrum of clinical conditions and comorbidities. Secondary infections, such as sinonasal mucormycosis, have become more frequent due to COVID-19-related immunosuppression and its subsequent treatments. Skull base osteomyelitis is another potentially fatal infection that is prevalent among immunocompromised individuals. Angiotensin-Converting Enzyme 2 (ACE2) receptors in the external auditory canal may also be implicated in cases of external otitis linked to COVID-19. Case Report: This report discusses two cases of treatment-resistant external otitis and skull base osteomyelitis in two elderly, immunosuppressed patients (with diabetes mellitus and chronic renal failure) who had previously been treated for COVID-19. In both cases, neither topical nor intravenous antibiotic treatments were effective, leading to referrals for hyperbaric oxygen therapy. Conclusion: For patients exhibiting persistent ear discharge and a history of COVID-19, it is imperative to avoid underestimating a potential diagnosis of skull base osteomyelitis and to pursue early imaging.
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