Evidence map›Paper›PMID 41256628›Full record

ArticlebioRxiv : the preprint server for biology2025

Long-range coupling regulates stator dynamics in the bacterial flagellar motor.

Shabduli A Sawant, I Can Kazan, Brennen M Wise, S Banu Ozkan, Navish Wadhwa

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shabduli A SawantBiodesign Center for Mechanisms of Evolution, Arizona State University, Tempe, AZ 85287, USA.ORCID 0000-0003-2768-1996
I Can KazanCenter for Biological Physics, Arizona State University, Tempe, AZ 85287, USA.ORCID 0000-0003-2593-4179
Brennen M WiseBiodesign Center for Mechanisms of Evolution, Arizona State University, Tempe, AZ 85287, USA.
S Banu OzkanCenter for Biological Physics, Arizona State University, Tempe, AZ 85287, USA.
Navish WadhwaBiodesign Center for Mechanisms of Evolution, Arizona State University, Tempe, AZ 85287, USA.ORCID 0000-0002-3514-5256

Funding

Using dynamic network models to quantitatively predict changes in binding affinity/specificity that arise from long-range amino acid substitutionsR01GM147635 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI OZKAN, SEFIKA BANU, SWINT-KRUSE, LISKIN · 2022 to 2025
$1.8M
Identifying the mechanisms of mechanosensing by the bacterial flagellar motorR00GM134124 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI WADHWA, NAVISH · 2023 to 2025
$747k
NIGMS NIH HHS R00 GM134124NIGMS NIH HHS R01 GM147635
6 · The paper itself

Abstract

The bacterial flagellar motor is driven by stator complexes that couple ion flux to torque generation. Active stators dynamically exchange with a membrane pool in a load-dependent manner, with off-rates decreasing as motor load increases. Each stator comprises of MotA, which engages the rotor, and MotB, whose periplasmic domain anchors the complex to the peptidoglycan. But how external load regulates this anchoring remains unclear. Here, we show that long-range couplings within the

Indexed as

bacterial flagellar motorco-evolutiondynamic couplingmechanosensingmolecular motorprotein dynamics

Identifiers

PMID41256628
PMCPMC12621912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.