Evidence map›Paper›PMID 41256607›Full record

ArticlebioRxiv : the preprint server for biology2025

Distributed neural computation and the evolution of the first brains.

Vikram Chandra, Mehrana R Nejad, Allison P Kann, Ananya Salem, Karl A P Hill, L Mahadevan, Mansi Srivastava

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vikram ChandraDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge MA 02138.ORCID 0000-0002-8020-0664
Mehrana R NejadSchool of Engineering and Applied Sciences, Harvard University, Cambridge MA 02138.ORCID 0000-0002-4670-9141
Allison P KannDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge MA 02138.ORCID 0000-0003-0111-9081
Ananya SalemDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge MA 02138.
Karl A P HillDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge MA 02138.
L MahadevanDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge MA 02138.ORCID 0000-0002-5114-0519
Mansi SrivastavaDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge MA 02138.ORCID 0000-0002-2126-8634

Funding

Quantifying organism-environment interactions in a new model system for neuroscienceR34DA061984 · NIDA · HARVARD UNIVERSITY · PI Mansi Srivastava · 2025 to 2026
$754k
NIDA NIH HHS R34 DA061984
6 · The paper itself

Abstract

Brains likely evolved from diffuse nerve nets in the Precambrian, but we do not know what the first brains looked like or how they were organized. Acoel worms, the sister lineage to all other animals with brains, offer a window into this transition. We studied the three-banded panther worm

Identifiers

PMID41256607
PMCPMC12621834

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.