Evidence map›Paper›PMID 41256579›Full record

ArticlebioRxiv : the preprint server for biology2025

Increased sensitivity to myopia and altered retinal ON/OFF balance in a mouse model lacking

Baptiste Wilmet, Christelle Michiels, Jingyi Zhang, Awen Louboutin, Sanja Boranijasevic, Helen Frederiksen, Jacques Callebert, Juliette Varin, Marie-Laure Gimenez, Catherine Morgans and 7 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Baptiste WilmetSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.ORCID 0009-0003-0058-0199
Christelle MichielsSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.ORCID 0000-0002-7193-5642
Jingyi ZhangSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.
Awen LouboutinSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.ORCID 0009-0001-2587-3495
Sanja BoranijasevicSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.ORCID 0009-0009-2191-0007
Helen FrederiksenSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.
Jacques CallebertService of Biochemistry and Molecular Biology, INSERM U942, Hospital Lariboisière, APHP, Paris, France.ORCID 0000-0002-5622-851X
Juliette VarinSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.ORCID 0000-0002-6842-9757
Marie-Laure GimenezSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.
Catherine MorgansChemical Physiology and Pharmacology, Oregon Health and Science University, Portland, Oregon, USA.ORCID 0000-0002-7287-3447
Robert DuvoisinChemical Physiology and Pharmacology, Oregon Health and Science University, Portland, Oregon, USA.ORCID 0000-0001-9603-7948
Linda HoranStrathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland.
Robin PlevinStrathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland.ORCID 0000-0002-7849-1220
Serge PicaudSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.ORCID 0000-0002-0548-5145
Olivier MarreSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.ORCID 0000-0002-0090-6190
Isabelle AudoSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.ORCID 0000-0003-0698-5309
Christina ZeitzSorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.ORCID 0000-0002-3510-1712

Funding

Molecular mechanisms of retinal ON-bipolar cell signalingR01EY029985 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI DUVOISIN, ROBERT M, MORGANS, CATHERINE W · 2019 to 2023
$2.6M
NEI NIH HHS R01 EY029985
6 · The paper itself

Abstract

Myopia, influenced by environmental and genetic factors, occurs when the emmetropization process fails to stop, causing excessive eyeball growth. Highly myopic animal models lacking a functional ON-pathway identified

Indexed as

Biological SciencecCSNBdopamineelectroretinographymyopiaNeuroscienceRetina

Identifiers

PMID41256579
PMCPMC12621960

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.