Evidence map›Paper›PMID 41256522›Full record

ArticlebioRxiv : the preprint server for biology2025

Tobramycin enhances

Jodi M Corley, Jack H Congel, Kelsey C Haist, Alma E Ochoa, Kenneth C Malcolm, William J Janssen, Jerry A Nick, Katherine B Hisert

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Jodi M CorleyDepartment of Medicine, National Jewish Health, Denver, CO 80206.ORCID 0000-0002-7734-7331
Jack H CongelDepartment of Medicine, National Jewish Health, Denver, CO 80206.
Kelsey C HaistDepartment of Medicine, National Jewish Health, Denver, CO 80206.
Alma E OchoaDepartment of Medicine, National Jewish Health, Denver, CO 80206.
Kenneth C MalcolmDepartment of Medicine, National Jewish Health, Denver, CO 80206.
William J JanssenDepartment of Medicine, National Jewish Health, Denver, CO 80206.
Jerry A NickDepartment of Medicine, National Jewish Health, Denver, CO 80206.
Katherine B HisertDepartment of Medicine, National Jewish Health, Denver, CO 80206.

Funding

GM-CSF, macrophages, and susceptibility to Mycobacterium abscessus pulmonary infectionR01HL167956 · NHLBI · NATIONAL JEWISH HEALTH · PI Katherine B Hisert · 2023 to 2026
$2.4M
NHLBI NIH HHS R01 HL167956
6 · The paper itself

Abstract

Nontuberculous mycobacteria (NTM) are opportunistic pathogens that cause pulmonary disease (PD) in people with bronchiectasis and other chronic airways diseases. Difficulty treating and eradicating NTM-PD highlights the need for improved understanding of bacterial mechanisms to establish chronic infections. People with the genetic disorder cystic fibrosis (CF) develop bronchiectasis and are the population at highest risk of NTM-PD, caused mainly by

Indexed as

antibiotic off-target effectsBiological Sciencesmacrophage survivalMicrobiologyMycobacterium abscessustranscriptional regulationWhiB7 regulon

Identifiers

PMID41256522
PMCPMC12621869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.