Evidence map›Paper›PMID 41256475›Full record

ArticlebioRxiv : the preprint server for biology2025

An Essential Adaptor for Apicoplast Fission and Inheritance in Malaria Parasites.

James Blauwkamp, Krithika Rajaram, Sophia R Staggers, Oliver Harrigan, Emma H Doud, Wei Xu, Hangjun Ke, Sean T Prigge, Stella Y Sun, Sabrina Absalon

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

James BlauwkampIndiana University School of Medicine, Department of Biochemistry Molecular Biology and Pharmacology, Indianapolis.ORCID 0000-0002-7639-2800
Krithika RajaramJohns Hopkins Bloomberg School of Public Health, Department of Molecular Microbiology and Immunology, Baltimore.ORCID 0000-0003-4830-5471
Sophia R StaggersUniversity of Pittsburgh, Department of Structural Biology, Pittsburgh.ORCID 0000-0002-8157-6372
Oliver HarriganIndiana University School of Medicine, Department of Biochemistry Molecular Biology and Pharmacology, Indianapolis.ORCID 0009-0003-6240-3518
Emma H DoudIndiana University School of Medicine, Department of Biochemistry Molecular Biology and Pharmacology, Indianapolis.ORCID 0000-0003-0049-0073
Wei XuCenter for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia.
Hangjun KeCenter for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia.ORCID 0000-0002-2006-3987
Sean T PriggeJohns Hopkins Bloomberg School of Public Health, Department of Molecular Microbiology and Immunology, Baltimore.ORCID 0000-0001-9684-1733
Stella Y SunUniversity of Pittsburgh, Department of Structural Biology, Pittsburgh.ORCID 0000-0001-9004-8494
Sabrina AbsalonIndiana University School of Medicine, Department of Biochemistry Molecular Biology and Pharmacology, Indianapolis.ORCID 0000-0003-2468-8156

Funding

Tumor Microenvironment and Metastasis ProgramP30CA082709 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI David W Clapp · 1999 to 2026
$59.3M
Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Determinants of apicoplast maintenance in malaria parasitesR01AI125534 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Sean Taylor PRIGGE · 2016 to 2026
$3.9M
Cryo-electron microscopeS10OD025009 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CONWAY, JAMES F. · 2018 to 2018
$2.0M
Proton pumping and energy metabolism of the ring stage malaria parasitesR01AI184855 · NIAID · DREXEL UNIVERSITY · PI Hangjun Ke · 2024 to 2026
$1.7M
Direct electron detecting (DED) cameraS10OD019995 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CONWAY, JAMES F. · 2015 to 2015
$548k
PfVP1, a battery of the malaria parasite, is critical for ring stage developmentR21AI156735 · NIAID · DREXEL UNIVERSITY · PI KE, HANGJUN · 2021 to 2022
$414k
NCATS NIH HHS UL1 TR002529NCI NIH HHS P30 CA082709NIAID NIH HHS R01 AI125534NIAID NIH HHS R01 AI184855NIAID NIH HHS R21 AI156735NIH HHS S10 OD019995NIH HHS S10 OD025009
6 · The paper itself

Abstract

Blood-stage

Identifiers

PMID41256475
PMCPMC12621961

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.