Evidence map›Paper›PMID 41256443›Full record

ArticlebioRxiv : the preprint server for biology2025

TUSC3 serves as a rate-limiting gatekeeper of a glycan-mediated ER Triage Checkpoint for BMP4/Dpp.

Antonio Galeone, Emilio Solazzo, Francesco Lavezzari, Seung-Yeop Han, Bruna My, Riccardo Rizzo, Giuseppe Gigli, Hamed Jafar-Nejad, Thomas Vaccari

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Antonio GaleoneInstitute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce, Italy; Tecnomed Puglia - Tecnopolo per la medicina di precisione (Biotech Lecce Hub), Lecce, Italy.ORCID 0000-0002-8678-7726
Emilio SolazzoInstitute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce, Italy; Tecnomed Puglia - Tecnopolo per la medicina di precisione (Biotech Lecce Hub), Lecce, Italy.
Francesco LavezzariDepartment of Biosciences, University of Milan, Milan, Italy.
Seung-Yeop HanDepartment of Molecular & Human Genetics, Baylor College of Medicine, Houston, USA.
Bruna MyDepartment of Mathematics and Physics, University of Salento, Lecce, Italy.
Riccardo RizzoInstitute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce, Italy; Tecnomed Puglia - Tecnopolo per la medicina di precisione (Biotech Lecce Hub), Lecce, Italy.
Giuseppe GigliInstitute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce, Italy; Tecnomed Puglia - Tecnopolo per la medicina di precisione (Biotech Lecce Hub), Lecce, Italy.
Hamed Jafar-NejadDepartment of Molecular & Human Genetics, Baylor College of Medicine, Houston, USA.ORCID 0000-0001-6403-3379
Thomas VaccariDepartment of Biosciences, University of Milan, Milan, Italy.ORCID 0000-0002-6231-7105

Funding

Roles of Glycosylation and Deglycosylation During Animal DevelopmentR35GM130317 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI Hamed Jafar-Nejad · 2019 to 2026
$3.7M
NIGMS NIH HHS R35 GM130317
6 · The paper itself

Abstract

Trimming of the three glucose residues decorating nascent

Indexed as

BMP signalingdeglycosylationDrosophilaEndoplasmic reticulumGlycosylationQuality control

Identifiers

PMID41256443
PMCPMC12621667

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.