ArticleWorld journal of gastrointestinal endoscopy2025
Diagnosis and management of a rare case of esophageal epidermoid metaplasia: A case report.
Article in World journal of gastrointestinal endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundEsophageal epidermoid metaplasia (EEM) is a rare potentially premalignant oesophageal lesion characterized by a dense granular layer with overlying hyperorthokeratosis resembling the epidermis of skin. Given the low prevalence, data to guide management also remains sparse. CASE SUMMARY: We highlight a case of a 60-year-old male who presented with gastroesophageal reflux disease symptoms 2 years after an index gastroscopy which showed C0M1 Barrett's oesophagus. The repeat gastroscopy detected a 15 mm oesophageal epidermoid metaplasia on a background of stable Barrett's esophagus. This was rather peculiar as the images form his index gastroscopy 2 years prior did not reveal any suspicious oesophageal mucosal abnormality. He underwent a successful endoscopic mucosal resection within 3 months with a surveillance gastroscopy scheduled 6 months later. The cases of confirmed EEM are very low. One study demonstrated out of 1048 consecutive oesophageal biopsies and resections for any indication, only two were EEM (0.19%). It was also noted that the prevalence of epidermoid metaplasia was significantly higher (
conclusionThis association necessitates careful consideration when determining resection
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