Evidence map›Paper›PMID 41256286›Full record

SynthesisFrontiers in public health2025

Meta-analysis of factors influencing depression in cervical cancer patients.

Rong Wang, Bang Liu, Si-Wen Wei, Yi-Ran Liu, Yi Zhong, Li Han, Huai-Qing Luo

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rong WangDepartment of Pathophysiology, School of Basic Medical Sciences, Hunan Normal University, Changsha, Hunan, China.
Bang LiuChangsha Maternal and Child Health Care Hospital Affiliated to Hunan Normal University, Changsha, Hunan, China.
Si-Wen WeiJishou University School of Medicine, Jishou, Hunan, China.
Yi-Ran LiuDepartment of Pathophysiology, School of Basic Medical Sciences, Hunan Normal University, Changsha, Hunan, China.
Yi ZhongHunan Provincial University Key Laboratory of the Fundamental and Clinical Research on Functional Nucleic Acid, Changsha Medical University, Changsha, Hunan, China.
Li HanHunan Provincial University Key Laboratory of the Fundamental and Clinical Research on Functional Nucleic Acid, Changsha Medical University, Changsha, Hunan, China.
Huai-Qing LuoDepartment of Pathophysiology, School of Basic Medical Sciences, Hunan Normal University, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Depression in cervical cancer (CC) patients concurrently compromises disease management and quality of life. However, significant discrepancies persist among existing studies regarding the determinants of depression in this population worldwide. To address this gap, this study employs meta-analysis to systematically identify and synthesize the contributing factors to depression among cervical cancer patients. Aim: To provide evidence-based references for mitigating depression risk among cervical cancer patients. Methods: Literature was searched in databases including CNKI, Wanfang, VIP, CBM, Web of Science, PubMed, and EMBASE from their inception until March 2025. The literature was screened, selected, quality assessed, and data extracted and analyzed. Meta-analysis was conducted using Revman 5.4 and Stata 18 software, with odds ratios (OR) and their 95% confidence intervals (CI) as the observed indicators. Results: A total of 1,108 articles were retrieved, with 15 articles ultimately included in the analysis. The results indicate that low educational attainment (OR = 3.25, 95% CI: 2.02-5.22), age ≥45 years (OR = 1.67, 95% CI: 1.09-2.55), inter-household monthly income disparity (OR = 3.06, 95% CI: 1.87-5.00), advanced tumor stage (OR = 1.99, 95% CI: 1.28-3.11), low social support (OR = 2.48, 95% CI: 1.95-3.16), moderate to severe pain (OR = 2.86, 95% CI: 1.76-4.65), limited disease awareness (OR = 2.58, 95% CI: 1.88-3.55), and undergoing hysterectomy (OR = 4.69, 95% CI: 3.03-7.24) are significant risk factors for depression in cervical cancer patients. Conclusion: The occurrence of depression in cervical cancer patients is influenced by multiple factors. Healthcare professionals and family members should conduct comprehensive assessments of patients' conditions to implement targeted prevention and intervention measures, thereby enhancing the psychological wellbeing of patients. Systematic review registration: https://inplasy.com/, identifier: INPLASY202560039.

Indexed as

DepressionUterine Cervical NeoplasmsFemaleHumansQuality of LifeRisk Factorscase-control studycervical cancerdepressioninfluencing factorsmeta-analysis

Identifiers

PMID41256286
PMCPMC12620220

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.