ArticleFrontiers in public health2025
Mortality burden and epidemiology of procedure- and device-related healthcare-associated infections in the United States, 1999-2023: a CDC WONDER analysis.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Etiologic Patterns and Evolution of Healthcare-Associated Infections in the Pandemic and Post-Pandemic Periods: A County-Level Multicenter Study from Southeastern Romania.Antibiotics (Basel, Switzerland) · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Procedure- and device-related healthcare-associated infections (PD-HAIs) are a major cause of preventable hospital mortality, yet population-level data on long-term trends remain limited. This study aims to evaluate national PD-HAI mortality trends and subgroup disparities in the United States from 1999 to 2023. Methods: This descriptive study analyzed PD-HAI-related mortality in the United States from 1999 to 2023 using the CDC Wide-ranging Online Data for Epidemiologic Research (WONDER) Multiple Cause of Death database. Deaths involving PD-HAIs were identified using ICD-10 codes. Age-adjusted mortality rates (AAMRs) were calculated per 100,000 population using the 2000 U.S. standard population. Temporal trends were assessed using Joinpoint regression to estimate annual percent changes (APCs) and average annual percent changes (AAPCs) with 95% confidence intervals (CIs). Analyses were stratified by age, sex, race, region, urbanization, and state. Results: From 1999 to 2023, PD-HAI-related mortality declined markedly nationwide, with AAMRs falling from 1.62 to 0.77 per 100,000 and an overall AAPC of -3.02% ( Conclusion: Despite national declines in PD-HAI mortality, trends have been less consistent since 2014, and significant geographic and demographic disparities persist. Sustained, state-tailored infection-prevention efforts-prioritizing jurisdictions with little or no progress-are needed as a matter of health equity to further reduce preventable deaths.
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