ArticleSmall science2025
Intraoperative Bioprinting for Craniomaxillofacial Bone Reconstruction in Rats and Sheep.
Article in Small science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Challenges and opportunities in generating microvasculature using bioprinting techniques.npj biomedical innovations · 2026Review
- Three-tier framework for high-throughput biofabrication: Integrating 3D bioprinting, assistive platforms, and translational opportunities.Bioactive materials · 2026Review
- 3D bioprinting of cell-laden constructs: technologies, bioink design, and biomedical applications.Biomedical materials (Bristol, England) · 2025Review
- Intraoperative Bioprinting for Craniomaxillofacial Bone Reconstruction in Rats and Sheep.Small science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Craniomaxillofacial reconstruction is challenging due to the requirement for diverse manual surgical interventions, which significantly increase as the defect volume enlarges. To address these concerns, we utilized intraoperative bioprinting (IOB) to reconstruct cranial bone defects in surgical settings. We formulated an innovative collagen-based bioink supplemented with human adipose-derived stem cells (hADSCs) or bone morphogenetic protein-2 (BMP-2). The concentration and dispersion state of collagen along with hADSCs were precisely adjusted to enhance cytocompatibility, bioprintability, and osteogenic activities. IOB was first performed via a 3-axis bioprinter on a rat model having a critical-sized calvarial defect (39.3 mm
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.