ArticlePostepy dermatologii i alergologii2025
Regeneration of the skin of oncology patients after radiation therapy using upcycled fish collagen.
Article in Postepy dermatologii i alergologii, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Oncological therapy is a very complex process. An accurate diagnosis is the first and most important stage of therapy for the patient as it allows the medical staff to determine what treatment is necessary and how to plan it. Cancer treatment is now widely recognized as holistic, in which the body is viewed as one interconnected system. Cancer therapy should not focus on just one area of care, but should also include treatment support such as proper nutrition, pain management, psychological care, rehabilitation and nursing. Cancer therapy, despite its effectiveness, has a number of negative effects felt mainly in the area of the skin subjected to irradiation. Side effects significantly affect the patient's quality of life through pain, discomfort and a negative impact on the aesthetic value of the skin. Aim: The aim of the article was to confirm the level of hydration, limit excessive water loss and regulate the pH value of the skin of patients after cancer treatment who were administered fish collagen. Material and methods: The cosmetic preparation collagen laminate obtained by ultrafiltration was tested on patients who underwent therapy at the University Hospital in Zielona Gora and who underwent radiotherapy. Patients are currently no longer undergoing treatment. The research group of 50 women suffered from breast cancer ( Results: Already after the first use, the device's skin hydration level increases by 5 a.u. In the next month it increased by 15 a.u. and in the fourth month it increased by 30 IU. Staff skin hydration levels increased linearly over time. After 5 parameters enabling 55 [a.u.] and after 6 a.m., another one until 6 a.m. [a.u.]. The average TEWL value measured in patients after radiotherapy was 40 g/m Conclusions: It was confirmed that the product tested for an oncological patient has an appropriate level of skin hydration, supports the reconstruction of the skin and its energy barrier by reducing transepidermal water loss and restoring appropriate pH values.
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