ArticleJournal of clinical practice and research2024
Investigation of Patients Receiving Ceftazidime-Avibactam (CZA) in an Intensive Care Unit: A Retrospective Study from a Tertiary Hospital.
Article in Journal of clinical practice and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Objective: This study aimed to examine the clinical characteristics and prognosis of patients receiving ceftazidime-avibactam (CZA) treatment in an intensive care unit (ICU). Materials and Methods: This observational, cross-sectional study was conducted with patients hospitalized in the ICU between June 2021 and April 2023. Among 1,900 patients, a total of 65 were identified to have received CZA treatment. All patients receiving this treatment were included in the study. We recorded patients' demographic data and comorbid diseases. We also investigated clinical outcomes in the ICU, such as sepsis, the requirement for mechanical ventilation (MV), mortality rates, and clinical features regarding infections. Results: Of the 65 patients, 69.2% were male, with an average age of 65±15 years. The overall mortality rate was 70.8%. The most common type of infection and the most frequently isolated pathogen were pneumonia (61.5%) and Conclusion: Our findings suggest that the development of septic shock, the requirement for mechanical ventilation (MV), and high APACHE-II and Sequential Organ Failure Assessment (SOFA) scores, and low GCS scores may be indicators of poor prognosis for patients requiring CZA.
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