ReviewJournal of clinical practice and research2024
Propionic Acidemia, Cardiomyopathies, and Arrhythmias.
Review in Journal of clinical practice and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Integrated Genomic and Transcriptomic Analysis Reveals the Genetic Basis and Causal Association Between Obesity and Atrial Fibrillation.Diabetes, obesity & metabolism · 2026Article
- Particular Aspects of Cardiac Rhythm Disorders in Symptomatic Children and Adolescents.Children (Basel, Switzerland) · 2026Article
- Effects of Qili Qiangxin granules in combination with Entresto on quantitative parameters of myocardial motion in patients with cardiomyopathy in end-stage renal disease.BMC cardiovascular disorders · 2026Article
- Metabolomic analysis reveals the role of gut microbiota metabolic disorders in heart failure due to congenital heart disease.Scientific reports · 2026Article
- An optimized Langendorff-free method for isolation and characterization of primary adult cardiomyocytes.BMC cardiovascular disorders · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systemic acid-base imbalances significantly influence the heart, both clinically and experimentally. Extensive knowledge exists regarding the impact of pH on cardiac function, yet the role of organic anions accumulating in acidosis is less explored. In severe metabolic acidosis cases, such as hereditary organic acidemias, these organic compounds can reach millimolar concentrations in blood and other body fluids, exerting significant physiological effects on the heart. Cardiomyopathies and arrhythmias are common in patients with organic acidemia, although the underlying pathophysiological processes remain unclear. Research into organic anion physiology, particularly concerning propionate - which accumulates in propionic acidemia (PA), a form of organic acidemia commonly associated with cardiac illness - has increased substantially in recent years. The purpose of this review is to provide an overview of the cardiac sequelae observed in PA patients who suffer from cardiac diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.